2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro-
METHYL 3-(CYCLOPROPYLAMINO)-2-(2,4-DICHLORO-5-FLUOROBENZOYL)ACRYLATE
CAS: 105392-26-5
Molecular Formula: C14H12Cl2FNO3
2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro- - Names and Identifiers
2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro- - Physico-chemical Properties
| Molecular Formula | C14H12Cl2FNO3 |
| Molar Mass | 332.15 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Melting Point | 150-154°C(lit.) |
| Boling Point | 468.4±45.0 °C(Predicted) |
| Flash Point | 237.1°C |
| Vapor Presure | 6.02E-09mmHg at 25°C |
| pKa | 2.56±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.579 |
| MDL | MFCD02683487 |
| Physical and Chemical Properties | WGK Germany:3 |
| Use | Intermediates for the manufacture of ciprofloxacin |
2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro- - Introduction
Methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-cyclopropylamine acrylate is an organic compound with the following properties:
1. appearance: is a colorless to yellow liquid.
2. Solubility: Soluble in common organic solvents, such as methanol, ethanol and dimethylformamide.
3. Melting point: The melting point range is about -10°C to -15°C.
4. molecular formula: C12H11Cl2FNO2.
This compound is mainly used in the field of medicine, as an organic synthesis intermediate, for the preparation of drugs and pesticides. It can be synthesized by the following steps:
1. methyl acrylate is reacted with 2,4-dichloro-5-fluorobenzoyl chloride to generate methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-cyclopropylamine acrylate.
2. The above product can be subjected to an acid-promoted hydrolysis reaction to obtain the target compound.
It should be noted that when preparing and using 2-(2,4-dichloro-5-fluorobenzoyl)-3-cyclopropylamine methyl acrylate, the following safety precautions should be paid attention:
1. Need to operate in a well-ventilated place to avoid inhaling its vapor or gas.
2. Wear appropriate protective equipment such as gloves, goggles and protective clothing when using the compound.
3. Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water and seek medical assistance.
4. Store this compound in a dry, cool and airtight container, away from ignition and other flammable substances.
5. Avoid contact with strong oxidants and strong acids to prevent dangerous reactions.
1. appearance: is a colorless to yellow liquid.
2. Solubility: Soluble in common organic solvents, such as methanol, ethanol and dimethylformamide.
3. Melting point: The melting point range is about -10°C to -15°C.
4. molecular formula: C12H11Cl2FNO2.
This compound is mainly used in the field of medicine, as an organic synthesis intermediate, for the preparation of drugs and pesticides. It can be synthesized by the following steps:
1. methyl acrylate is reacted with 2,4-dichloro-5-fluorobenzoyl chloride to generate methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-cyclopropylamine acrylate.
2. The above product can be subjected to an acid-promoted hydrolysis reaction to obtain the target compound.
It should be noted that when preparing and using 2-(2,4-dichloro-5-fluorobenzoyl)-3-cyclopropylamine methyl acrylate, the following safety precautions should be paid attention:
1. Need to operate in a well-ventilated place to avoid inhaling its vapor or gas.
2. Wear appropriate protective equipment such as gloves, goggles and protective clothing when using the compound.
3. Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water and seek medical assistance.
4. Store this compound in a dry, cool and airtight container, away from ignition and other flammable substances.
5. Avoid contact with strong oxidants and strong acids to prevent dangerous reactions.
Last Update：2024-04-09 21:21:28
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Product Name: 2-(2,4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic acid, methyl ester, mixture of isomers Visit Supplier Webpage Request for quotation
CAS: 105392-26-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 105392-26-5
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QQ: 3008007409
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View History
2-(2.4-Dichloro-5-fluorobenzoyl)-3-cyclopropylaminoacrylic-methylester-7-chloro-
苯甲酰基二茂铁
ethyl 2-(2-cyano-3-fluorophenyl)-2,2-difluoroacetate
16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
methylacrylate
112559-81-6
苯甲酰基二茂铁
ethyl 2-(2-cyano-3-fluorophenyl)-2,2-difluoroacetate
16α,17α-环氧-3β-羟基-16β-甲基孕甾-5-烯-20-酮
methylacrylate
112559-81-6