2-(4-METHOXYBENZYLAMINO)PYRIMIDINE
N-(4-methoxybenzyl)pyrimidin-2-amine
CAS: 6957-21-7
Molecular Formula: C12H13N3O
2-(4-METHOXYBENZYLAMINO)PYRIMIDINE - Names and Identifiers
| Name | N-(4-methoxybenzyl)pyrimidin-2-amine |
| Synonyms | 2-(4-METHOXYBENZYLAMINO)PYRIMIDINE N-(4-Methoxybenzyl)-2-pyrimidinamine N-(4-methoxybenzyl)pyrimidin-2-amine N-(4-Methoxybenzyl)pyrimidin-2-amine N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine 2-Pyrimidinamine, N-[(4-methoxyphenyl)methyl]- |
| CAS | 6957-21-7 |
| InChI | InChI=1/C12H13N3O/c1-16-11-5-3-10(4-6-11)9-15-12-13-7-2-8-14-12/h2-8H,9H2,1H3,(H,13,14,15) |
2-(4-METHOXYBENZYLAMINO)PYRIMIDINE - Physico-chemical Properties
| Molecular Formula | C12H13N3O |
| Molar Mass | 215.25 |
| Density | 1.195±0.06 g/cm3(Predicted) |
| Melting Point | 97-99 °C |
| Boling Point | 175-176 °C(Press: 1.5-2 Torr) |
| Flash Point | 196.7°C |
| Vapor Presure | 1.16E-06mmHg at 25°C |
| pKa | 3.55±0.10(Predicted) |
| Refractive Index | 1.619 |
2-(4-METHOXYBENZYLAMINO)PYRIMIDINE - Introduction
N-(4-methoxybenzyl)pyrimidin-2-amine is an organic compound with the chemical formula C12H13N3O and a molecular weight of 215.25g/mol. It is a white crystalline powder.
Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane, slightly soluble in water
-melting point: about 120-122 degrees Celsius
Use:
N-(4-methoxybenzyl)pyrimidin-2-amine has important application value in the field of medicine, and can be used as drug intermediates, such as synthetic intermediates for anticancer drugs and antiviral drugs. In addition, it can also be used in biochemical research, organic synthesis and chemical analysis.
Preparation Method:
There are many methods for preparing N-(4-methoxybenzyl)pyrimidin-2-amine. A common method is to react 4-trimethopyrimidine with 2-aminopyrimidine in the presence of a base to obtain the target product.
Safety Information:
The use of N-(4-methoxybenzyl)pyrimidin-2-amine should follow laboratory safety procedures. It may cause irritation to the skin, eyes and respiratory tract, so wear appropriate protective gloves, goggles and respiratory protection when used. Avoid contact with oxidizing agents during storage and handling.
Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane, slightly soluble in water
-melting point: about 120-122 degrees Celsius
Use:
N-(4-methoxybenzyl)pyrimidin-2-amine has important application value in the field of medicine, and can be used as drug intermediates, such as synthetic intermediates for anticancer drugs and antiviral drugs. In addition, it can also be used in biochemical research, organic synthesis and chemical analysis.
Preparation Method:
There are many methods for preparing N-(4-methoxybenzyl)pyrimidin-2-amine. A common method is to react 4-trimethopyrimidine with 2-aminopyrimidine in the presence of a base to obtain the target product.
Safety Information:
The use of N-(4-methoxybenzyl)pyrimidin-2-amine should follow laboratory safety procedures. It may cause irritation to the skin, eyes and respiratory tract, so wear appropriate protective gloves, goggles and respiratory protection when used. Avoid contact with oxidizing agents during storage and handling.
Last Update：2024-04-09 20:52:54
