2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol - Names and Identifiers
2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol - Introduction
2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol is an organic compound with the chemical formula C10H10BrF2O2. The following are some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless to slightly yellow liquid
-Melting point: about 35-37 ° C
-Boiling point: About 140-142 ° C
-Density: about 1.565 g/mL
-Soluble: Soluble in some organic solvents such as ether and dichloromethane
Use:
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol is a commonly used raw material compound, which has many applications in the field of pharmaceutical synthesis and organic synthesis. For example, it can be used to synthesize biologically active molecules, pharmaceutical intermediates, etc.
Method:
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol is generally prepared by the method of organic synthetic chemistry, and the following is a possible synthetic route:
1. First, 2,2-difluoroacetic anhydride is reacted with 4-bromo-3-methoxyphenyl alcohol to produce 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetate.
2. Then, the obtained 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid ester is reduced with hydrogen to obtain the target product 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol.
Safety Information:
Some safety information for
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroethan-1-ol may include that it has low toxicity, may be irritating to the eyes, skin and respiratory tract, that swallowing should be avoided, avoid contact with strong oxidants. For detailed safety information, please refer to the relevant chemical safety information or consult a professional.
Last Update：2024-04-09 21:01:54