2-(Boc-aminomethyl)-piperidine

2-(Boc-aminomethyl)-piperidine - Names and Identifiers

Name	2-(Boc-aminomethyl)-piperidine
Synonyms	Boc-Pip(2-AM)*HCl SALOR-INT L480339-1EA 2-Boc-aminomethyl-piperidine 1-BOC-2-AMINOMETHYLPIPERIDINE 2-(Boc-aminomethyl)-piperidine 2-(N-BOC-AMINOMETHYL)PIPERIDINE 2-(N'-BOC-AMINOMETHYL)-PIPERIDINE (R,S)-2-(BOC-AMINOMETHYL)-PIPERIDINE tert-butyl 2-piperidinylmethylcarbamate TERT-BUTYL PIPERIDIN-2-YL-METHYLCARBAMATE PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER Carbamic acid, (2-piperidinylmethyl)-, 1,1-dimethylethyl ester (R,S)-1-t-Butyloxycarbonyl-2-(aminomethyl)piperidine hydrochloride
CAS	141774-61-0
InChI	InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-8-9-6-4-5-7-12-9/h9,12H,4-8H2,1-3H3,(H,13,14)

2-(Boc-aminomethyl)-piperidine - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	0.981±0.06 g/cm3(Predicted)
Melting Point	93-97°C
Boling Point	321.8±15.0 °C(Predicted)
Flash Point	148.4°C
Vapor Presure	0.00029mmHg at 25°C
Appearance	Solid
pKa	12.84±0.46(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.457
MDL	MFCD02181068

2-(Boc-aminomethyl)-piperidine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection.
WGK Germany	3
HS Code	29333990
Hazard Note	Irritant

2-(Boc-aminomethyl)-piperidine - Introduction

2-(tert-butoxycarbonylaminomethyl)-piperidine is a compound having the formula C12H20N2O2. The following is a description of its nature, use, formulation and safety information:

Nature:
2-(tert-butoxycarbonylaminomethyl)-piperidine is a colorless to pale yellow solid, which is soluble in organic solvents. It is a weakly alkaline compound that is only slightly soluble in water.

Use:
The compound is often used as a reaction reagent in organic synthesis, especially for the synthesis of other organic compounds, such as drugs and pesticides. It can be used as a quaternary ammonium salt reagent for catalytic oxidation and substitution reactions.

Preparation Method:
2-(tert-butoxycarbonylaminomethyl)-piperidine can be obtained by reacting 2-hydroxymethylpiperidine with tert-butylfluoroacetyl chloride. The specific preparation method can be adjusted according to the conditions and needs of the laboratory.

Safety Information:
The following safety precautions should be taken when using or handling 2-(tert-butoxycarbonylaminomethyl)-piperidine:
1. The compound can cause eye and skin irritation, so use appropriate protective measures during operation, such as gloves, goggles and protective clothing.
2. Avoid inhaling the dust or gas of the compound, so operate in a well-ventilated environment.
3. When storing the compound, it should be stored in a cool, dry place, away from fire and oxidizing agents.
4. If you ingest or come into contact with it, you should seek medical help immediately and bring the compound container or label.

Last Update：2024-04-09 20:49:11