2-ACETAMINO PHENOL
N-(2-hydroxyphenyl)acetamide
CAS: 614-80-2
Molecular Formula: C8H9NO2
2-ACETAMINO PHENOL - Names and Identifiers
| Name | N-(2-hydroxyphenyl)acetamide |
| Synonyms | O-ACETAMINOPHENOL 2-ACETAMIDOPHENOL 2-Acetamidophenol O-ACETAMIDOPHENOL 2-acetamido-pheno Acet-o-aminofenol 2-Acetamido Phenol O-ACETAMIDO PHENOL 2-ACETAMINO PHENOL 2-ACETYLAMINOPHENOL O-ACETAMIDOPHENOL 2-HYDROXYACETANILIDE O-HYDROXYACETANILIDE 2'-hydroxy-acetanilid 2'-HYDROXYACETANILIDE Acetanilide, 2'-hydroxy- o-alkyl acetophenylamine N-(2-hydroxyphenyl)acetamide 2-hydroxyanilidkyselinyoctove 2-Hydroxyanilid kyseliny octove Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide) |
| CAS | 614-80-2 |
| EINECS | 210-396-9 |
| InChI | InChI=1/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10) |
2-ACETAMINO PHENOL - Physico-chemical Properties
| Molecular Formula | C8H9NO2 |
| Molar Mass | 151.16 |
| Density | 1.2023 (rough estimate) |
| Melting Point | 205-210°C(lit.) |
| Boling Point | 273.17°C (rough estimate) |
| Flash Point | 161.3°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 3.64E-05mmHg at 25°C |
| Appearance | Bright brown powder |
| Color | Off-white to beige to brown |
| BRN | 607592 |
| pKa | 9.35±0.35(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides. |
| Refractive Index | 1.5810 (estimate) |
| MDL | MFCD00002181 |
| Physical and Chemical Properties | White crystalline or powder. Melting Point 209 ℃, soluble in hot water and ethanol, micro-soluble in cold water. |
| Use | For organic synthesis, the pharmaceutical industry, also used as a stabilizer for hydrogen peroxide |
2-ACETAMINO PHENOL - Risk and Safety
| Risk Codes | R36/38 - Irritating to eyes and skin. R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | AE4025000 |
| FLUKA BRAND F CODES | 1-8 |
| TSCA | Yes |
| HS Code | 29242995 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
2-ACETAMINO PHENOL - Introduction
Soluble in ethanol and alkaline solution, slightly soluble in methanol.
Last Update：2022-10-16 17:27:07
2-ACETAMINO PHENOL - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | 2-acetamide phenol (Orthocetamol) is an Ortho regioisomer of Paracetamol (4-acetamide phenol). 2-acetamidophanol is a promising analgesic and anti-arthritic drug. |
| Use | It is used in organic synthesis, pharmaceutical industry (an intermediate of the new antitumor drug pyrimidine phenyl mustard), and also used as a stabilizer of hydrogen peroxide. used in organic synthesis, pharmaceutical industry, also used as stabilizer of hydrogen peroxide |
| production method | O-aminophenol, acetic acid and acetic anhydride are mixed (I. E., there is crystallization), then directly in the fire to dissolve all, stop heating, cooling, diluted with water, precipitation crystallization filter dry, with 70~80 deg C of ethanol recrystallization to obtain the finished product. |
Last Update：2024-04-09 21:21:28
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Spot supply
Product Name: Paracetamol Impurity 1（Paracetamol EP Impurity A） Visit Supplier Webpage Request for quotationCAS: 614-80-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: 2-Acetamidophenol Visit Supplier Webpage Request for quotationCAS: 614-80-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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