2-Acétylisonicotinate de méthyle - Names and Identifiers
2-Acétylisonicotinate de méthyle - Physico-chemical Properties
Molecular Formula | C9H9NO3
|
Molar Mass | 179.17 |
Density | 1.178±0.06 g/cm3(Predicted) |
Boling Point | 296.6±25.0 °C(Predicted) |
Flash Point | 133.173°C |
Vapor Presure | 0.001mmHg at 25°C |
pKa | 0.35±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.519 |
2-Acétylisonicotinate de méthyle - Introduction
2-Acetylisobutyryl Nicotinate is an organic compound with the following properties:
1. appearance and properties: 2-acetyl isonicotinic acid methyl ester is a colorless to pale yellow liquid. It has a sweet smell and is soluble in alcohol and organic solvents.
2. use: 2-acetylisonicotinic acid methyl ester commonly used as pharmaceutical intermediates. It can be used to synthesize various drugs, such as alnadol (Arnaudol) and metformin.
3. Preparation method: 2-acetyl isonicotinic acid methyl ester can be obtained by reacting isonicotinic acid with acetyl chloride. The reaction conditions may be carried out under basic conditions.
4. Safety Information: There is limited safety information regarding methyl 2-acetylisonicotinate. As a chemical, it should be stored in a dry, well-ventilated place, and away from fire and oxidants. Wear appropriate protective equipment to avoid contact with skin and eyes during use and handling. If inhaled or ingested, seek medical attention immediately. Specific safety handling and storage requirements shall be in accordance with the safety data sheets provided by the Supplier.
Last Update:2024-04-09 18:58:34