2-Acetamidophenylboronic Acid

2-Acetamidophenylboronic Acid - Names and Identifiers

Name	(2-Acetylaminophenyl)boronic acid
Synonyms	2-Acetamidophenylboronicacid 2-ACETAMIDOPHENYLBORONIC ACID 2-Acetamidophenylboronic acid O-ACETAMIDOPHENYLBORONIC ACID 2-Acetamidophenylboronic Acid 2-ACETAMIDOBENZENEBORONIC ACID 2-carbamoylbenzeneboronic acid 2-ACETYLAMINOPHENYLBORONIC ACID acetamidooxy(phenyl)borinic acid (2-Acetylaminophenyl)boronic acid Boronic acid, B-[2-(acetylaMino)phenyl]-
CAS	169760-16-1
InChI	InChI=1/C8H10BNO3/c1-6(11)10-8-5-3-2-4-7(8)9(12)13/h2-5,12-13H,1H3,(H,10,11)

2-Acetamidophenylboronic Acid - Physico-chemical Properties

Molecular Formula

C8H10BNO3

Molar Mass

178.98

Density

1.23±0.1 g/cm3(Predicted)

Melting Point

>300 °C

pKa

8.46±0.53(Predicted)

Storage Condition

2-8°C

Refractive Index

1.553

Physical and Chemical Properties

2-Acetamidophenylboronic Acid - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29319090
Hazard Note	Harmful
Hazard Class	IRRITANT

2-Acetamidophenylboronic Acid - Introduction

(2-Acetylaminophenyl)boronic acid (also known as N-(2-acetylphenyl) boronic acid) is an Organoboron compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C10H11BO3
-Molecular weight: 182.00g/mol
-Melting point: 150-152 ° C
-Solubility: Soluble in water and common organic solvents

Use:
-Coordination chemistry:(2-Acetylaminophenyl)boronic acid can be used as a ligand to form complexes with transition metals for catalytic reactions and the synthesis of hybrid materials.
-Organic synthesis: The compound has active acid-base properties and is commonly used in acid-catalyzed reactions in organic synthesis or reactions under acidic conditions.
-Pharmaceutical field:(2-Acetylaminophenyl)boronic acid and its derivatives are widely used in drug research and development, some of which have anti-cancer, anti-inflammatory and antibacterial properties.

Method:
- (2-Acetylaminophenyl)boronic acid can be obtained by reacting Phenylboronic acid with acetamide. The reaction is usually carried out in a dry organic solvent, and the reaction is carried out at an appropriate temperature to produce (2-Acetylaminophenyl)boronic acid.

Safety Information:
- (2-Acetylaminophenyl)boronic acid has no obvious safety risk under normal use conditions. However, as laboratory reagents, appropriate laboratory manipulations and personal protective measures should be taken to avoid direct contact with skin and eyes. If taken by mistake or inhaled in large quantities, seek medical attention immediately and provide details of the compound.

Last Update：2024-04-09 20:45:29