2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride - Names and Identifiers
2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride - Physico-chemical Properties
Molecular Formula | C8H17ClN2O
|
Molar Mass | 192.68638 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD09028974 |
2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride - Risk and Safety
2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride - Introduction
2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride, chemical formula C8H17ClN2O, which is the hydrochloride salt of a compound.
Properties of the compound include:
-Appearance: White crystal or crystalline powder
-Melting point: 92-98°C
-Solubility: Soluble in water, ethanol and chloroform
The main uses of 2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride are:
-Drug intermediate: It can be used as an intermediate for the synthesis of certain drugs, such as for the synthesis of the heart disease drug Proprilone (Perindopril)
-Chemical reagent: it can be used for amino protection reagents and crosslinking agents in organic synthesis reactions
2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride is generally prepared by the following steps:
1. cyanate esterification reaction of aminoacetaldehyde: aminoacetaldehyde reacts with cyanate ester to generate aminoacetaldehyde cyanate ester.
2. pyrolysis of aminoacetaldehyde cyanate ester: heating reaction of aminoacetaldehyde cyanate ester in alkaline alcohol to obtain 2-Amino-1-(1-piperidinyl)-1-propanone.
3. Hydrochlorination of 2-Amino-1-(1-piperidinyl)-1-propanone: Reaction of 2-Amino-1-(1-piperidinyl)-1-propanone with hydrochloric acid produces 2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride.
About safety information:
- 2-Amino-1-(1-piperidinyl)-1-propanone hydrochloride is a chemical that needs to be stored and handled in accordance with safe operating procedures.
-Wear appropriate personal protective equipment during use, such as protective glasses, protective gloves and laboratory coats.
-Avoid contact with skin and eyes, and avoid inhalation or ingestion of the compound.
-For unintended contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When handling and storing, please refer to the relevant Safety Data Sheet and follow the appropriate laboratory safety procedures.
Last Update:2024-04-09 20:00:08