2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN
2-butenylmagnesium chloride
CAS: 22649-70-3
Molecular Formula: C21H25N
2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN - Names and Identifiers
| Name | 2-butenylmagnesium chloride |
| Synonyms | 2-Butenylchloromagnesium Chloro(2-butenyl) magnesium 2-butenylmagnesium chloride 2-BUTENYLMAGNESIUM CHLORIDE 2-Butenylmagnesium chloride solution 2-Butenylmagnesium chloride, 0.5M in MeTHF 2-Butenylmagnesium chloride solution 0.5 in THF 2-Butenylmagnesium chloride 0.5M solution in 2-MeTHF 2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN |
| CAS | 22649-70-3 |
| InChI | InChI=1/C4H7.ClH.Mg/c1-3-4-2;;/h3-4H,1H2,2H3;1H;/q;;+1/p-1/b4-3+;;/rC4H7ClMg/c1-2-3-4-6-5/h2-3H,4H2,1H3/b3-2+ |
2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN - Physico-chemical Properties
| Molecular Formula | C21H25N |
| Molar Mass | 291.43 |
| Density | 0.921g/mLat 25°C |
| Flash Point | −22°F |
2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14/15 - R19 - May form explosive peroxides R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. R15 - Contact with water liberates extremely flammable gases |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 3 |
| HS Code | 29319090 |
2-BUTENYLMAGNESIUM CHLORIDE, 1.0M SOLUTI ON IN TETRAHYDROFURAN - Introduction
2-butenylmagnesium chloride is an organometallic compound with the chemical formula C4H9ClMg. It is a colorless liquid with a special pungent odor. It reacts very easily with water in the air, so it must be stored and handled under anhydrous conditions.
2-butenylmagnesium chloride is commonly used as a reagent in organic synthesis. It can be used as an addition reagent for addition reactions with alcohols, ketones and aldehydes. In addition, it can also be used to construct carbon-carbon bonds, such as Gilman reduction reaction and Giese reaction. It is an important intermediate in the synthesis of organic compounds.
The preparation of 2-butenylmagnesium chloride generally requires the reaction of 2-butenyl with magnesium chloride. Excess magnesium chloride may be added in an anhydrous solvent, such as tetrahydrofuran (THF), and stirred, followed by slow dropwise addition of butene. After completion of the reaction, the target product can be obtained by filtration or distillation.
Safety precautions are required when using 2-butenylmagnesium chloride. Because it is very sensitive to water, it may react violently and easily cause fire or explosion. Operate in a moisture-proof environment and wear suitable protective equipment such as chemical protective gloves, goggles and protective clothing. When stored, it should be kept in a sealed container, away from fire and combustibles. In addition, avoid inhaling its vapor or contact with the skin to avoid irritation or injury. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
2-butenylmagnesium chloride is commonly used as a reagent in organic synthesis. It can be used as an addition reagent for addition reactions with alcohols, ketones and aldehydes. In addition, it can also be used to construct carbon-carbon bonds, such as Gilman reduction reaction and Giese reaction. It is an important intermediate in the synthesis of organic compounds.
The preparation of 2-butenylmagnesium chloride generally requires the reaction of 2-butenyl with magnesium chloride. Excess magnesium chloride may be added in an anhydrous solvent, such as tetrahydrofuran (THF), and stirred, followed by slow dropwise addition of butene. After completion of the reaction, the target product can be obtained by filtration or distillation.
Safety precautions are required when using 2-butenylmagnesium chloride. Because it is very sensitive to water, it may react violently and easily cause fire or explosion. Operate in a moisture-proof environment and wear suitable protective equipment such as chemical protective gloves, goggles and protective clothing. When stored, it should be kept in a sealed container, away from fire and combustibles. In addition, avoid inhaling its vapor or contact with the skin to avoid irritation or injury. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
