2-Benzofurancarboxylic acid, 5-methoxy-

2-Benzofurancarboxylic acid, 5-methoxy- - Names and Identifiers

Name	5-Methoxybenzofuran-2-carboxylic acid
Synonyms	AKOS BBS-00007942 TIMTEC-BB SBB010862 ASINEX-REAG BAS 03293533 5-Methoxy-2-Benzofurancarboxylic Acid 5-METHOXYBENZOFURAN-2-CARBOXYLIC ACID 5-Methoxybenzofuran-2-carboxylic acid 2-Benzofurancarboxylic acid, 5-methoxy- 5-METHOXY-1-BENZOFURAN-2-CARBOXYLIC ACID 5-methoxy-1-benzofuran-2-carboxylic acid
CAS	10242-08-7
InChI	InChI=1/C10H8O4/c1-13-7-2-3-8-6(4-7)5-9(14-8)10(11)12/h2-5H,1H3,(H,11,12)

2-Benzofurancarboxylic acid, 5-methoxy- - Physico-chemical Properties

Molecular Formula	C10H8O4
Molar Mass	192.17
Density	1.345±0.06 g/cm3(Predicted)
Melting Point	212 °C
Boling Point	352.4±22.0 °C(Predicted)
Flash Point	166.907°C
Vapor Presure	0mmHg at 25°C
pKa	3.06±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.617

2-Benzofurancarboxylic acid, 5-methoxy- - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

2-Benzofurancarboxylic acid, 5-methoxy- - Introduction

5-methoxybenzofuran-2-carboxylic acid (5-oxetanyl acid) is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
5-methoxybenzofuran-2-carboxylic acid is a white solid with a benzofuran ring and a carboxyl functional group. It is stable at room temperature and soluble in a variety of organic solvents.

Use:
5-methoxybenzofuran-2-carboxylic acid has important pharmaceutical intermediate properties and can be used to synthesize various drugs. It is widely used in the field of medicine, commonly used in the synthesis of analgesic drugs, anti-inflammatory drugs and anti-cancer drugs. In addition, it can also be used as dyes and chemical reagents.

Preparation Method:
The preparation method of 5-methoxybenzofuran-2-carboxylic acid is mainly realized by the reaction of p-methoxybenzene and benzofuran-2-carboxylic acid. In general, methoxybenzene is first reacted with a basic catalyst to give the methoxybenzofuran, and then the carboxylic acid function is introduced by an acylation reaction under appropriate conditions.

Safety Information:
Under the correct operating conditions, 5-methoxybenzofuran-2-carboxylic acid is generally considered to be a relatively safe compound. However, as organic compounds, appropriate safety measures still need to be taken. During the operation, wear gloves, goggles and laboratory coats, and ensure that the operation is carried out in a well-ventilated place. At the same time, avoid contact with skin or eyes, and avoid inhaling its dust or steam. In case of accidental exposure or inhalation, seek medical help immediately.

Last Update：2024-04-09 21:11:58