2-Bromo-2-methylpropionamide

2-Bromo-2-methylpropionamide - Names and Identifiers

Name	2-BROMO-2-METHYLPROPANAMIDE
Synonyms	2-Bromoisobutyramide 2-Bromo-2-methylpropiomide 2-BROMO-2-METHYLPROPANAMIDE 2-Bromo-2-methylpropionamide 2-Bromo-2,2-dimethylacetamide PropanaMide,2-broMo-2-Methyl-
CAS	7462-74-0
InChIKey	WTRIMJTZOOLIFZ-UHFFFAOYSA-N

2-Bromo-2-methylpropionamide - Physico-chemical Properties

Molecular Formula	C4H8BrNO
Molar Mass	166.02
Density	1.4132 (rough estimate)
Melting Point	145-149 °C
Boling Point	240.0±23.0 °C(Predicted)
pKa	14.79±0.50(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.5500 (estimate)
MDL	MFCD08234837

2-Bromo-2-methylpropionamide - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Safety Description	24/25 - Avoid contact with skin and eyes.
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
HS Code	29241990
Hazard Class	IRRITANT
Packing Group	Ⅲ

2-Bromo-2-methylpropionamide - Upstream Downstream Industry

Raw Materials

3-hydroxy-2,2-diMethyl-3-phenylpropanaMide
2-bromo-2-methylpropanenitrile
2-Bromoisobutyrylchloride
Benzaldehyde
2-Bromoisobutyryl Bromide
Ethyl 2-bromoisobutyrate

2-Bromo-2-methylpropionamide - Introduction

2-BROMO-2-METHYLPROPANAMIDE is an organic compound with the chemical formula C5H10BrNO. The following is a description of the properties, uses, formulation and safety information of 2-bromo-2-methylpropylamide:

Nature:
-2-bromo-2-methylpropylamide is a colorless or light yellow liquid.
-It is soluble in water at room temperature.
-It has a pungent smell.
-It has a density of 1.454g/cm³.
-Its boiling point is 222-223°C.

Use:
-2-bromo-2-methylpropylamide is commonly used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize biologically active compounds.
-The compound has certain application value in the field of medicine and pesticide.

Method:
The synthesis method of 2-bromo-2-methylpropylamide can be carried out by the following steps:
1.2-methyl propionaldehyde reacts with bromoacetic acid to generate allyl alcohol bromide salt.
2. Under alkaline conditions, the bromide salt of allyl alcohol is dehydrated to generate 2-bromoisobutene.
3. Finally, 2-bromo-2-methylpropylamide is prepared by reacting 2-bromo-2-bromo-2-methylpropylamide with ammonia.

Safety Information:
-2-bromo-2-methylpropylamide is a corrosive substance, avoid contact with skin and eyes.
-During use, you should wear appropriate protective equipment, including gloves, protective glasses and laboratory coats.
-Avoid inhaling its vapor and ensure that it is operated in a well-ventilated place.
-Keep and dispose of the compound properly, following local regulations and guidelines.

Last Update：2024-04-09 21:00:56