2-Bromo-N-(4-ethoxyphenyl)propanamide
2-Bromo-N-(4-ethoxyphenyl)propanamide
CAS: 109098-43-3
Molecular Formula: C11H14BrNO2
2-Bromo-N-(4-ethoxyphenyl)propanamide - Names and Identifiers
2-Bromo-N-(4-ethoxyphenyl)propanamide - Physico-chemical Properties
| Molecular Formula | C11H14BrNO2 |
| Molar Mass | 272.14 |
| Density | 1.409±0.06 g/cm3(Predicted) |
| Melting Point | 136 °C |
| Boling Point | 401.4±30.0 °C(Predicted) |
| pKa | 12.10±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09063109 |
2-Bromo-N-(4-ethoxyphenyl)propanamide - Risk and Safety
| Hazard Class | IRRITANT |
2-Bromo-N-(4-ethoxyphenyl)propanamide - Introduction
2-Bromo-N-(4-ethoxyphenyl)propanamide is an organic compound whose chemical formula is C11H14BrNO2. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
1. appearance: white crystalline powder or crystal.
2. Melting point: about 80-85°C.
3. Solubility: Soluble in organic solvents such as alcohol, ether and ketone, insoluble in water.
Use:
1. Intermediate compound: 2-Bromo-N-(4-ethoxyphenyl)propanamide is commonly used as an intermediate in organic synthesis.
2. Pharmaceutical field: It can be used to synthesize some biologically active molecules, such as drugs or drug candidate compounds.
Preparation Method:
The synthesis method of 2-Bromo-N-(4-ethoxyphenyl)propanamide is as follows:
First, reacting propionamide with an ether reagent (such as ethoxy bromide) to obtain 2-bromo-N-propionamide;
Then, the product obtained by the reaction again is reacted with phenyl bromide with an ethoxy group at the para-position to generate 2-Bromo-N-(4-ethoxyphenyl)propanamide.
Safety Information:
1. This compound should be used in a laboratory environment, following safe procedures and avoiding contact with skin, eyes or inhalation of its powder.
2. Please keep it away from heat and flame.
3. avoid contact with oxidants to prevent dangerous reactions.
4. Wear appropriate personal protective equipment such as laboratory gloves, glasses, and protective clothing during use or handling.
Please note that this information is for reference only and that laboratory safety manuals and chemical-specific safety data sheets are required.
Nature:
1. appearance: white crystalline powder or crystal.
2. Melting point: about 80-85°C.
3. Solubility: Soluble in organic solvents such as alcohol, ether and ketone, insoluble in water.
Use:
1. Intermediate compound: 2-Bromo-N-(4-ethoxyphenyl)propanamide is commonly used as an intermediate in organic synthesis.
2. Pharmaceutical field: It can be used to synthesize some biologically active molecules, such as drugs or drug candidate compounds.
Preparation Method:
The synthesis method of 2-Bromo-N-(4-ethoxyphenyl)propanamide is as follows:
First, reacting propionamide with an ether reagent (such as ethoxy bromide) to obtain 2-bromo-N-propionamide;
Then, the product obtained by the reaction again is reacted with phenyl bromide with an ethoxy group at the para-position to generate 2-Bromo-N-(4-ethoxyphenyl)propanamide.
Safety Information:
1. This compound should be used in a laboratory environment, following safe procedures and avoiding contact with skin, eyes or inhalation of its powder.
2. Please keep it away from heat and flame.
3. avoid contact with oxidants to prevent dangerous reactions.
4. Wear appropriate personal protective equipment such as laboratory gloves, glasses, and protective clothing during use or handling.
Please note that this information is for reference only and that laboratory safety manuals and chemical-specific safety data sheets are required.
Last Update：2024-04-09 21:01:54
