2-CHLORO-1-FLUORO-4-(TRIFLUOROMETHYL)BENZENE

2-CHLORO-1-FLUORO-4-(TRIFLUOROMETHYL)BENZENE - Names and Identifiers

Name	Methyl 4-(trifluoromethoxy)benzoate
Synonyms	RARECHEM AL BF 0284 Methyl 4-(trifluoromethoxy)benzoate METHYL 4-(TRIFLUOROMETHOXY)BENZOATE 2-methyl-4-(trifluoromethoxy)benzoate 2-chloro-1-fluoro-4-(trifluoromethyl)benzene Benzoic acid, 4-(trifluoromethoxy)-, methyl ester
CAS	780-31-4
EINECS	200-563-4
InChI	InChI=1/C7H3ClF4/c8-5-3-4(7(10,11)12)1-2-6(5)9/h1-3H

2-CHLORO-1-FLUORO-4-(TRIFLUOROMETHYL)BENZENE - Physico-chemical Properties

Molecular Formula	C9H7F3O3
Molar Mass	220.15
Density	1.312±0.06 g/cm3(Predicted)
Boling Point	78 °C
Flash Point	42.2°C
Vapor Presure	8.99mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.432

2-CHLORO-1-FLUORO-4-(TRIFLUOROMETHYL)BENZENE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

2-CHLORO-1-FLUORO-4-(TRIFLUOROMETHYL)BENZENE - Introduction

Methyl 4-(trifluoromethoxy)benzoate(Methyl 4-(trifluoromethoxy)benzoate) is an organic compound. Its chemical formula is C9H7F3O3.

Nature:
Methyl trifluoromethoxybenzoate is a colorless liquid with a sweet fragrance. It has a lower boiling point and higher solubility, soluble in a variety of organic solvents.

Use:
Methyl trifluoromethoxybenzoate is often used as an important intermediate in organic synthesis reactions. It can be used in the synthesis of pesticides, pharmaceuticals and other organic compounds. Specific applications include the synthesis of anti-inflammatory drugs, fungicides, etc.

Preparation Method:
There are two main methods for the preparation of methyl trifluoromethoxybenzoate. One is obtained by reacting methyl p-hydroxybenzoate with trifluoromethanol to obtain the product after dehydration treatment. The other is obtained by reacting methyl p-methoxybenzoate with trifluoromethyl bromide.

Safety Information:
The toxicity of trifluoromethoxybenzoic acid methyl ester is low, but it is still necessary to pay attention to safe operation. Avoid contact with skin, eyes and respiratory tract. If there is contact, rinse immediately with plenty of water. When stored, should be sealed in a cool, dry place, away from the fire and oxidant.

Last Update：2024-04-09 02:00:48