2-CHLORO-3-FLUOROPHENYLBORONIC ACID

2-CHLORO-3-FLUOROPHENYLBORONIC ACID - Names and Identifiers

Name	2-Chloro-3-fluorophenylboronic acid
Synonyms	SKL185 1-Borono-2-chloro-3-fluorobenzene 2-Chloro-3-fluorophenylboronic acid 2-CHLORO-3-FLUOROPHENYLBORONIC ACID 2-CHLORO-3-FLUOROBENZENEBORONIC ACID (2-Chloro-3-fluorophenyl)boronic acid Boronic acid, B-(2-chloro-3-fluorophenyl)- (2-Chloro-3-fluorophenyl)boronic Acid (contains varying amounts of Anhydride)
CAS	871329-52-1
InChI	InChI=1/C6H5BClFO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,10-11H

2-CHLORO-3-FLUOROPHENYLBORONIC ACID - Physico-chemical Properties

Molecular Formula	C6H5BClFO2
Molar Mass	174.37
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	80-84
Boling Point	313.4±52.0 °C(Predicted)
Flash Point	143.367°C
Water Solubility	Slightly soluble in water.
Vapor Presure	0mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	7.20±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.533

2-CHLORO-3-FLUOROPHENYLBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
HS Code	29310099
Hazard Note	Irritant

2-CHLORO-3-FLUOROPHENYLBORONIC ACID - Introduction

Acid is an organic compound with the chemical formula C6H5BClF2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a colorless to yellowish solid.
-Solubility: Its solubility in water is low, but it has better solubility in organic solvents.
-Stability: The compound is relatively stable at room temperature.

Use:
-catalyst: acid is often used as a catalyst in organic synthesis. It can be used to synthesize drugs, pesticides, dyes and other organic compounds.
-Lithium-ion battery: It is also used as the electrolyte of lithium-ion batteries and has a certain conductivity.

Preparation Method:
The preparation of acid can be carried out by the following steps:
1. First, 2-chloro-3-fluorophenyl borate is heated to react with an acid.
2. After the reaction, the product is extracted and purified by crystallization or column chromatography.

Safety Information:
-Allergenicity: acid may cause allergic reactions to certain people, and personal protective measures should be paid attention to when contacting.
-Toxicity: The compound has low toxicity, but it should still avoid ingestion or inhalation, and avoid direct contact with skin, eyes, etc.
-Storage: Store acid in a dry, well-ventilated and dark place, away from combustibles and oxidants.

Last Update：2024-04-09 21:01:54