2-CHLORO-5-NITROCINNAMIC ACID

2-CHLORO-5-NITROCINNAMIC ACID - Names and Identifiers

Name	2-Chloro-5-nitrocinnamic acid
Synonyms	5-Nitro-2-chlorocinnamic acid 2-Chloro-5-nitrocinnamic acid 2-CHLORO-5-NITROCINNAMIC ACID 3-(2-CHLORO-5-NITROPHENYL)ACRYLIC ACID 3-(2-Chloro-5-nitrophenyl)propenoic acid (2E)-3-(2-chloro-5-nitrophenyl)prop-2-enoate (2E)-3-(2-chloro-5-nitrophenyl)prop-2-enoic acid 2-Chloro-5-nitrocinnamic acid, predominantly trans, pure
CAS	36015-19-7
InChI	InChI=1/C9H6ClNO4/c10-8-3-2-7(11(14)15)5-6(8)1-4-9(12)13/h1-5H,(H,12,13)/p-1/b4-1+

2-CHLORO-5-NITROCINNAMIC ACID - Physico-chemical Properties

Molecular Formula	C9H6ClNO4
Molar Mass	227.6
Density	1.529±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	218-222 °C
Boling Point	401.7°C at 760 mmHg
Flash Point	196.7°C
Vapor Presure	3.57E-07mmHg at 25°C
BRN	1972431
Storage Condition	Room Temprature
Refractive Index	1.6000 (estimate)
MDL	MFCD00063312

2-CHLORO-5-NITROCINNAMIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	24/25 - Avoid contact with skin and eyes.
Hazard Class	IRRITANT

2-CHLORO-5-NITROCINNAMIC ACID - Introduction

2-Chloro-5-nitrocinnamic acid is an organic compound with the chemical formula C9H6ClNO4. It is a yellow crystal that is solid at room temperature.

The following are the properties of 2-Chloro-5-nitrocinnamic acid:
-Melting point: 215-220°C
-Boiling point: 408.8°C
-melting: insoluble in water, soluble in organic solvents such as ethanol, chloroform
-Density: 1.487g/cm3
-Molecular weight: 225.6g/mol

2-Chloro-5-nitrocinnamic acid is mainly used as follows:
-Used as a chemical reagent: The compound can be used in organic synthesis reactions, such as the synthesis of amino acids, the preparation of catalysts, etc.
-Used in pharmaceutical research: Due to its special molecular structure, 2-Chloro-5-nitrocinnamic acid has potential application prospects in the field of pharmaceutical research.

As for the method of preparing 2-Chloro-5-nitrocinnamic acid, a common preparation method is to react cinnamic acid with sulfuryl chloride to generate 2-sulfonylcinnamic acid, and then react with chloro nitro compound to obtain 2-Chloro-5-nitrocinnamic acid. The specific synthesis steps can be adjusted according to the experimental conditions.

When using 2-Chloro-5-nitrocinnamic acid, you need to pay attention to the following safety information:
-due to its special chemical properties, the correct wear of personal protective equipment, such as protective glasses, gloves and experimental coat.
-Avoid contact with skin and inhalation of dust or gas. If contact occurs, flush the affected area immediately with plenty of water and seek medical advice.
-When storing and carrying, care should be taken to avoid mixing with other chemicals to avoid reaction or danger.
-Follow laboratory safety regulations during operation and ensure adequate ventilation.

Both the preparation and use of 2-Chloro-5-nitrocinnamic acid need to be carried out in a safe laboratory environment and after understanding the complete material properties and operating procedures.

Last Update：2024-04-09 22:09:11