2-Chloro-5-pyriMidinecarbonitril

2-Chloro-5-pyriMidinecarbonitril - Names and Identifiers

Name	5-Pyrimidinecarbonitrile, 2-chloro- (7CI,8CI)
Synonyms	2-Chloro-5-pyriMidinecarb... 2-Chloro-5-pyriMidinecarbonitril 2-chloropyrimidine-5-carbonitrile 2-Chloro-5-pyrimidinecarbonitrile 5-Pyrimidinecarbonitrile, 2-chloro- 5-Pyrimidinecarbonitrile, 2-chloro- (7CI,8CI)
CAS	1753-50-0
InChI	InChI=1/C5H2ClN3/c6-5-8-2-4(1-7)3-9-5/h2-3H

2-Chloro-5-pyriMidinecarbonitril - Physico-chemical Properties

Molecular Formula	C5H2ClN3
Molar Mass	139.54
Density	1.43±0.1 g/cm3(Predicted)
Melting Point	130-132 °C
Boling Point	331.3±15.0 °C(Predicted)
Flash Point	154.2°C
Vapor Presure	0.000157mmHg at 25°C
pKa	-4.13±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.568

2-Chloro-5-pyriMidinecarbonitril - Introduction

5-pyrimidinecarbonitril, 2-choro- (7CI,8CI) is an organic compound with the chemical formula C4H2ClN3. The following is a description of its nature, use, preparation and safety information:

Properties: 5-Pyrimidinecarbonitrile, 2-chloro- (7CI,8CI) is a white crystalline or crystalline powder with a unique cyano and chlorine-based structure. It has a melting point of about 204-205°C and is sparingly soluble in water and in organic solvents such as ethanol and ether.

use: 5-pyrimidinecarbonitril, 2-choro- (7CI,8CI) is commonly used as pesticide and pharmaceutical intermediates. As a pesticide, it has the ability to inhibit weeds and pests and can be used for seed treatment, foliar spraying and soil treatment. As a pharmaceutical intermediate, it can be used in the synthesis of some biologically active compounds, such as anti-tumor drugs and antiviral drugs.

preparation method: the preparation of 5-pyrimidinecarbonitril, 2-chloro- (7CI,8CI) can usually be obtained by reacting 2-chloro -5-nitropyrimidine with sodium bisulfite in water. 2-Chloro-5-nitropyrimidine and sodium bisulfite were first dissolved in water and the reaction mixture was then heated. After the completion of the reaction, a pure product can be obtained by steps such as filtration and washing.

Safety information: 5-pyrimidinecarbonitril, 2-choro- (7CI,8CI) is relatively safe under general conditions of use, but some safety matters still need to be paid attention to during operation. It is an organic compound and should avoid contact with skin and eyes. Wear appropriate personal protective equipment, such as lab gloves, safety glasses, and lab coats, during operation. In addition, the storage and handling of this compound should be carried out in accordance with the relevant safety procedures, maintain good ventilation, and away from ignition and flammable materials.

Last Update：2024-04-09 02:00:43