2-Chloroacetamidine monohydrochloride
2-chloroacetamidine monohydrochloride
CAS: 10300-69-3
Molecular Formula: C2H6Cl2N2
2-Chloroacetamidine monohydrochloride - Names and Identifiers
2-Chloroacetamidine monohydrochloride - Physico-chemical Properties
| Molecular Formula | C2H6Cl2N2 |
| Molar Mass | 128.99 |
| Melting Point | 98-103°C(lit.) |
| Boling Point | 146.4°C at 760 mmHg |
| Flash Point | 42.4°C |
| Water Solubility | Insoluble in water. |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 4.64mmHg at 25°C |
| Appearance | Solid |
| BRN | 3678354 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| Sensitive | Moisture Sensitive |
| MDL | MFCD00053013 |
2-Chloroacetamidine monohydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN3261 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
2-Chloroacetamidine monohydrochloride - Introduction
Chloroacetamidine hydrochloride is an organic compound with the chemical formula C2H4ClN · HCl, which is a white crystalline solid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Chloroacetamidine hydrochloride is a solid that is readily soluble in water. When dissolved in water, a dehydration reaction occurs to produce the free form of chloroacetamidine.
-Its melting point is about 138-142°C, and its boiling point is about 203°C.
-Chloroacetamidine hydrochloric acid is an acidic solution, and its acidity mainly comes from the ions of hydrochloric acid.
Use:
-Chloroacetamidine hydrochloride can be used as a reagent in organic synthesis, and is commonly used as a catalyst for acylation reactions and acylation reactions.
-It can also be used to prepare other compounds, such as amino ketones, amides, etc.
Preparation Method:
The preparation method of chloroacetamidine hydrochloric acid is generally to react chloroacetic acid with dry ammonia, and then add hydrochloric acid for neutralization reaction. Specific preparation methods can be the following:
1. Dissolve chloroacetic acid in dry ether, and then add ammonia gas to obtain chloroacetamidine. The obtained chloroacetamidine was further added to hydrochloric acid to obtain chloroacetamidine hydrochloride.
2. add chloroacetic acid to dry methanol, and then add ammonia gas to react to generate chloroacetamidine. Finally, chloroacetamidine is added to hydrochloric acid to obtain chloroacetamidine hydrochloride.
Safety Information:
-Chloroacetamidine hydrochloride is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, wear protective glasses and gloves during use and ensure adequate ventilation.
-Avoid contact with organics, combustibles or oxidants during storage and handling to prevent fire or explosion.
-When using this compound, you should follow the safe operation procedures during use, and comply with relevant safety regulations and thinning conditions. Inappropriate operation may cause harm to the human body and the environment, so please operate under the guidance of professionals.
Nature:
-Chloroacetamidine hydrochloride is a solid that is readily soluble in water. When dissolved in water, a dehydration reaction occurs to produce the free form of chloroacetamidine.
-Its melting point is about 138-142°C, and its boiling point is about 203°C.
-Chloroacetamidine hydrochloric acid is an acidic solution, and its acidity mainly comes from the ions of hydrochloric acid.
Use:
-Chloroacetamidine hydrochloride can be used as a reagent in organic synthesis, and is commonly used as a catalyst for acylation reactions and acylation reactions.
-It can also be used to prepare other compounds, such as amino ketones, amides, etc.
Preparation Method:
The preparation method of chloroacetamidine hydrochloric acid is generally to react chloroacetic acid with dry ammonia, and then add hydrochloric acid for neutralization reaction. Specific preparation methods can be the following:
1. Dissolve chloroacetic acid in dry ether, and then add ammonia gas to obtain chloroacetamidine. The obtained chloroacetamidine was further added to hydrochloric acid to obtain chloroacetamidine hydrochloride.
2. add chloroacetic acid to dry methanol, and then add ammonia gas to react to generate chloroacetamidine. Finally, chloroacetamidine is added to hydrochloric acid to obtain chloroacetamidine hydrochloride.
Safety Information:
-Chloroacetamidine hydrochloride is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, wear protective glasses and gloves during use and ensure adequate ventilation.
-Avoid contact with organics, combustibles or oxidants during storage and handling to prevent fire or explosion.
-When using this compound, you should follow the safe operation procedures during use, and comply with relevant safety regulations and thinning conditions. Inappropriate operation may cause harm to the human body and the environment, so please operate under the guidance of professionals.
Last Update：2024-04-10 22:29:15
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