2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile - Names and Identifiers
2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile - Physico-chemical Properties
Molecular Formula | C6H3FN2
|
Molar Mass | 122.1 |
Density | 1.24 |
Melting Point | 72-74℃ |
Boling Point | 221℃ |
Flash Point | 88℃ |
Vapor Presure | 0.108mmHg at 25°C |
pKa | -1.44±0.10(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.509 |
2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile - Risk and Safety
2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile - Introduction
It is an organic compound with the chemical formula C6H3FN2. Its properties are as follows:
1. appearance: colorless liquid or solid.
2. Solubility: Soluble in many organic solvents, such as ethanol, ether and dichloromethane.
3. Melting point: about 50-54°C.
4. Boiling point: about 170-173°C.
It can be used as an important intermediate in organic synthesis and is widely used in the fields of medicine, pesticide and dye. It can be used to synthesize various fluorine-containing organic compounds, such as pyridines or fluorine-containing heterocyclic compounds. Since it contains a cyano group (C≡N), other organic compounds can also be synthesized from its reaction product.
Common methods of preparation include the following:
1. 2-Cyanopyridine and hydrogen fluoride react to get.
2. Pyridine hydrogen fluoride reacts to produce 4-fluoropyridine, which then reacts with hydrogen cyanide to obtain pyridine and pyridine.
Regarding safety information, the following should be noted when using this compound:
1. It belongs to organic cyanide, which has certain toxicity and should follow the safety operation procedures.
2. contact with the skin or inhalation of the compound may cause irritation, should avoid inhalation of its vapor.
3. in the use of the process should wear appropriate protective gloves, protective glasses and protective masks.
4. It should be operated in a well-ventilated place to avoid exposure to open flames and high temperatures.
5. should be stored in a cool, dry, ventilated place, away from oxidants and combustibles.
Last Update:2024-04-09 21:04:16