2-Deacetoxytaxinine B - Names and Identifiers
Name | 2-Deacetoxytaxinine B
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Synonyms | 2-Deacetoxytaxinine B 2-Propenoic acid, 3-phenyl-, (1S,3S,4aR,6R,11R,12R,12aS)-1,11,12-tris(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-8-oxo-6,10-methanobenzocyclodecen-3-yl ester, (2E)-
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CAS | 191547-12-3
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2-Deacetoxytaxinine B - Physico-chemical Properties
Molecular Formula | C35H42O9
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Molar Mass | 606.7 |
Density | 1.21±0.1 g/cm3(Predicted) |
Melting Point | 240 °C (decomp) |
Boling Point | 669.7±55.0 °C(Predicted) |
Appearance | Powder |
Storage Condition | 2-8℃ |
2-Deacetoxytaxinine B - Introduction
2-Deacetoxytaxinine B is a natural product, belonging to Taxol compounds, chemical name is (5α,13α)-2-acetoxy-5, 20-dihydroxy -7, 10-Dimethyl-11-alkyl-12, 16-diazataxane. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-Deacetoxytaxinine B is a white to light yellow solid.
-molecular formula: C29H41NO5
-Molecular weight: 483.65g/mol
-Melting point: 134-136 ° C
-Solubility: Soluble in chloroform and dichloromethane, slightly soluble in ethanol.
Use:
-Anti-tumor activity: 2-Deacetoxytaxinine B has anti-tumor activity and can be used as one of the candidate compounds for drug research and development.
Method:
The preparation method of-2-Deacetoxytaxinine B is relatively complicated and generally involves multi-step reaction synthesis.
-A method of synthesis is to start from paclitaxel, through a series of chemical reactions and substitution reactions, and finally synthesize 2-Deacetoxytaxinine B. Specific synthetic methods can be found in the relevant scientific literature.
Safety Information:
The toxicity and safety of-2-Deacetoxytaxinine B are not fully understood, and caution is required when using it.
-It is recommended to operate in a laboratory environment, strictly abide by the experimental safety regulations, and use appropriate protective equipment.
-This compound is only for scientific research and laboratory use, and is not suitable for direct use in human or animal treatment. Appropriate toxicological and biological assessments should be performed prior to use.
-Please store the compound properly, avoid contact with strong oxidizers, and keep away from ignition sources.
Last Update:2024-04-09 15:18:05