2-Demecolchicine D3 - Names and Identifiers
2-Demecolchicine D3 - Physico-chemical Properties
Molecular Formula | C21H23NO6
|
Molar Mass | 385.41042 |
Melting Point | 190-198°C |
Storage Condition | -20°C |
2-Demecolchicine D3 - Introduction
2-Demethyl Colchicine-d3 (2-demethyl-d3) is an important organic compound with the following properties:
1. Appearance: colorless crystal or powder substance.
2. Chemical formula: C22H21NO6-d3.
3. Molecular weight: 379.43g/mol.
4. Solubility: Soluble in alcohol and Ester solvents, slightly soluble in water.
5. Melting point: About 241-244 ° C.
2-Demethyl Colchicine-d3 are mainly used in scientific research and medicine. It is a colchicine labeled compound in which d3 represents a hydrogen atom replaced by heavy hydrogen (deuterium). This compound is commonly used in pharmacokinetic studies, drug metabolism and pharmacokinetic studies, etc.
The method for preparing 2-Demethyl Colchicine-d3 is as follows:
1. First, 2-Demethyl Colchicine (2-demethylcolchicine) is used as the starting material.
2. The starting material reacts with a deuterating reagent (such as sodium deuteride) to replace the hydrogen atoms with deuterium.
3. After suitable purification and crystallization process, 2-Demethyl Colchicine-d3 with high purity was obtained.
For safety information, note the following when using the 2-Demethyl Colchicine-d3:
1. The compound may be harmful to health, should follow the laboratory safety procedures, and use personal protective equipment (such as laboratory gloves, protective glasses, etc.).
2. Avoid inhalation or contact with skin, eyes or clothing. If contact occurs, rinse immediately with plenty of water and seek medical help.
3. The compound should be stored in a dry, cool place, away from fire and organic matter.
Last Update:2024-04-09 21:01:54