2-Fluoro-5-bromobenzyl bromide

2-Fluoro-5-bromobenzyl bromide - Names and Identifiers

Name	2-Fluoro-5-bromobenzyl bromide
Synonyms	2-Fluoro-5-broMobenz 2-Fluoro-5-broMobenl broMide 2-Fluoro-5-bromobenzyl bromide 5-Bromo-2-fluorobenzyl bromide 2-fluoro-5-broMobenzyl chloride 4-Brom-2-(brommethyl)-1-fluorbenzol 4-broMo-2-(broMoMethyl)-1-fluorobenzene 4-Bromo-2-(bromomethyl)-1-fluorobenzene benzene, 4-bromo-2-(bromomethyl)-1-fluoro- 4-Bromo-2-(bromomethyl)-1-fluorobenzene, alpha,5-Dibromo-2-fluorotoluene
CAS	99725-12-9
InChI	InChI=1/C7H5Br2F/c8-4-5-3-6(9)1-2-7(5)10/h1-3H,4H2

2-Fluoro-5-bromobenzyl bromide - Physico-chemical Properties

Molecular Formula	C7H5Br2F
Molar Mass	267.92
Density	1.923±0.06 g/cm3(Predicted)
Melting Point	35℃
Boling Point	126-136 °C(Press: 15 Torr)
Flash Point	107.06°C
Vapor Presure	0.029mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.583

2-Fluoro-5-bromobenzyl bromide - Introduction

2-Fluoro-5-bromobenzyl bromide is an organic compound with the chemical formula C7H5Br2F. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 2-Fluoro-5-bromobenzyl bromide as a colorless to pale yellow solid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane at room temperature, but it is difficult to dissolve in water.
-Melting point: Its melting point is about 50-52 degrees Celsius.
-Boiling point: Its boiling point is about 230 degrees Celsius.

Use:
- 2-Fluoro-5-bromobenzyl bromide can be used as an important intermediate in organic synthesis.
-It can be used to adjust the structure of certain drugs and improve their performance, such as the preparation process of anti-cancer drugs.
-It can also be used as raw materials in the fields of pesticides, dyes and medicines.

Preparation Method:
- 2-Fluoro-5-bromobenzyl bromide can be prepared by the following method: first brominate 2-fluorobenzyl, and then brominate to obtain the final product. Specifically, 2-fluorobenzyl is first brominated to form 2-bromobenzyl bromide, and then a second bromine atom is introduced by bromination to form 2-Fluoro-5-bromobenzyl bromide.

Safety Information:
- 2-Fluoro-5-bromobenzyl bromide is an organic halide, which has certain toxicity and irritation. Contact with skin, eyes and mucous membranes should be avoided.
-Wear appropriate personal protective equipment such as lab gloves, protective glasses and protective masks during use and handling.
-When storing, it should be kept in a dry, cool place, and away from fire and strong oxidants.
-Observe local laboratory safety practices and waste disposal regulations when handling the compound.

It should be noted that the safety and use of chemical substances may vary, so the latest scientific literature and relevant safety data should be consulted before use.

Last Update：2024-04-09 19:05:53