2-Iodo-4-pyridinecarboxylic acid

2-Iodo-4-pyridinecarboxylic acid - Names and Identifiers

Name	2-iodopyridine-4-carboxylic acid
Synonyms	2-Iodoisonicotinicaci 2-IODO-ISONICOTINIC ACID 2-Iodopyridine-4-carboxylic ac 2-Iodo-4-pyridinecarboxylic acid 2-iodopyridine-4-carboxylic acid 2-Iodopyridine-4-carboxylic acid 4-Pyridinecarboxylic acid, 2-iodo-
CAS	58481-10-0
EINECS	640-453-7
InChI	InChI=1/C6H4INO2/c7-5-3-4(6(9)10)1-2-8-5/h1-3H,(H,9,10)

2-Iodo-4-pyridinecarboxylic acid - Physico-chemical Properties

Molecular Formula	C6H4INO2
Molar Mass	249.01
Density	2.123±0.06 g/cm3(Predicted)
Melting Point	210-220°C
Boling Point	466.5±30.0 °C(Predicted)
Flash Point	235.958°C
Vapor Presure	0mmHg at 25°C
pKa	3.02±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Sensitive to light
Refractive Index	1.677
MDL	MFCD06800803

2-Iodo-4-pyridinecarboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Class	IRRITANT

2-Iodo-4-pyridinecarboxylic acid - Introduction

Acid is an organic compound with the chemical formula C6H4INO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-must acid is a solid, usually yellow to orange crystalline.
-It is soluble in some organic solvents, such as ethanol and dimethylformamide (DMF), but insoluble in water.
-The compound is relatively stable in the air, but will gradually decompose under strong light.

Use:
-acid is an important organic synthesis intermediate, which can be used to synthesize various organic compounds.
-It can be used as a raw material for drug synthesis, such as anti-tumor drugs, antibacterial drugs, etc.

Preparation Method:
There are many preparation methods for acid. Common methods include the heating reaction of pyridine iodide and 4-carboxylic acid, and the reaction of pyridine iodide and 4-carboxylic anhydride.
-During the preparation process, attention should be paid to controlling the reaction temperature and reaction time to avoid the occurrence of side reactions.

Safety Information:
-the acid may be irritating to the eyes, skin and respiratory tract.
-Wear appropriate personal protective equipment such as gloves, goggles and face shields during operation.
-When exposed to the compound, immediately flush the affected area with plenty of water and seek medical treatment.
-Follow the safe handling of chemicals and store and handle the compound properly.

Last Update：2024-04-09 19:05:50