2-Methyl-5-nitro-1H-imidazole-1-acetic acid ethyl ester - Names and Identifiers
2-Methyl-5-nitro-1H-imidazole-1-acetic acid ethyl ester - Physico-chemical Properties
Molecular Formula | C8H11N3O4
|
Molar Mass | 213.19 |
Storage Condition | 2-8°C |
2-Methyl-5-nitro-1H-imidazole-1-acetic acid ethyl ester - Introduction
Ethyl 2-methyl-5-nitro-1H-imidazole-1-acetate is an organic compound with the chemical formula C9H11N3O4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Methyl-5-nitro-1H-imidazole-1-ethyl acetate is a white to light yellow crystalline powder.
-Solubility: Soluble in common organic solvents, such as methanol, ethanol and ether.
Use:
-Pharmaceutical field: 2-methyl-5-nitro-1H-imidazole-1-ethyl acetate is an intermediate for the synthesis of drugs. It can be used in the preparation of antifungal and antitumor drugs, etc.
Preparation Method:
The preparation method of 2-methyl-5-nitro-1H-imidazole-1-ethyl acetate is as follows:
1.2-methyl -1H-imidazole and nitric acid are reacted under appropriate conditions to obtain 2-nitro -5-methyl -1H-imidazole.
2. 2-Nitro-5-methyl-1H-imidazole is reacted with ethyl chloroacetate under basic conditions to give ethyl 2-methyl-5-nitro-1H-imidazole-1-acetate.
Safety Information:
-2-methyl-5-nitro-1H-imidazole-1-ethyl acetate should be careful to prevent contact with strong oxidants during use and storage.
-When handling it should wear protective gloves, goggles and protective clothing, avoid direct contact with the skin and eyes.
-It should be operated in a well-ventilated place to avoid inhaling its dust.
-When disposing of waste, dispose of it properly in accordance with local regulations.
Last Update:2024-04-09 02:00:54