2-Methylthio-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
6-(Methylthio)pyridine-3-boronic acid pinacol ester
CAS: 849934-89-0
Molecular Formula: C12H18BNO2S
2-Methylthio-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
2-Methylthio-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
| Molecular Formula | C12H18BNO2S |
| Molar Mass | 251.15 |
| Density | 1.1g/cm3 |
| Melting Point | 165-168℃ |
| Boling Point | 362.2°C at 760 mmHg |
| Flash Point | 172.9°C |
| Vapor Presure | 4.1E-05mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.525 |
| MDL | MFCD09037495 |
2-Methylthio-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
6-(Methylthio)pyridine-3-boronic acid pinacol ester is an organic compound with the chemical formula C12H17BNO2S. It is a colorless to pale yellow solid, stable at room temperature.
Nature:
-Melting point: about 65-70 ℃
-Boiling point: about 293-294 ℃
-Density: approx. 1.24g/cm³
Use:
6-(Methylthio)pyridine-3-boronic acid pinacol ester is an important intermediate in organic synthesis. It is often used in metal-catalyzed reactions or reduction reactions, as a donor of borate esters, and can be used to synthesize biologically active compounds. It has a wide range of applications in drug synthesis, material science and natural product synthesis.
Preparation Method:
A common method of preparation is by reacting 6-(methylthio) pyridine with dimethyl borate. The reaction conditions can be optimized according to the specific needs. The reaction is typically carried out under an inert atmosphere, typically in an organic solvent such as dimethylformamide (DMF) or chloromethane.
Safety Information:
6-(Methylthio)pyridine-3-boronic acid pinacol ester is generally relatively safe under normal use conditions. However, as a chemical substance, some safety measures still need to be paid attention to during operation. Contact with skin and eyes should be avoided and appropriate personal protective equipment, such as lab gloves and goggles, should be worn during use. At the same time, use and storage should be careful to avoid contact with oxidants, acids or alkalis and other substances to avoid harmful substances or dangerous reactions. The safety data sheet (SDS) of the product should be read carefully before use and the corresponding operating and handling instructions should be followed.
Nature:
-Melting point: about 65-70 ℃
-Boiling point: about 293-294 ℃
-Density: approx. 1.24g/cm³
Use:
6-(Methylthio)pyridine-3-boronic acid pinacol ester is an important intermediate in organic synthesis. It is often used in metal-catalyzed reactions or reduction reactions, as a donor of borate esters, and can be used to synthesize biologically active compounds. It has a wide range of applications in drug synthesis, material science and natural product synthesis.
Preparation Method:
A common method of preparation is by reacting 6-(methylthio) pyridine with dimethyl borate. The reaction conditions can be optimized according to the specific needs. The reaction is typically carried out under an inert atmosphere, typically in an organic solvent such as dimethylformamide (DMF) or chloromethane.
Safety Information:
6-(Methylthio)pyridine-3-boronic acid pinacol ester is generally relatively safe under normal use conditions. However, as a chemical substance, some safety measures still need to be paid attention to during operation. Contact with skin and eyes should be avoided and appropriate personal protective equipment, such as lab gloves and goggles, should be worn during use. At the same time, use and storage should be careful to avoid contact with oxidants, acids or alkalis and other substances to avoid harmful substances or dangerous reactions. The safety data sheet (SDS) of the product should be read carefully before use and the corresponding operating and handling instructions should be followed.
Last Update：2024-04-09 21:11:58
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Product Name: 6-(Methylthio)Pyridine-3-Boronic Acid Pinacol Ester Visit Supplier Webpage Request for quotation
CAS: 849934-89-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 849934-89-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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