introduction | vitamin K3(MNB) MNB combines nicotinamide molecular groups to replace sodium ions and three crystal waters in MSB on the basis of MSB. on the one hand, it eliminates the existence of water molecules, the factor causing product instability, and on the other hand, macromolecular groups block the path of isomer transformation and inhibit the generation of isomers, at the same time, the presence of auxiliary groups is conducive to the transformation and absorption of VK3 in organisms. On the basis of MSB, MNB combines nicotinamide molecular groups to replace sodium ions and three crystal waters in MSB. On the one hand, it eliminates the existence of water molecules, the factor that triggers product instability, and on the other hand, macromolecular groups It avoids the path of isomer transformation and inhibits the formation of isomers. At the same time, the presence of auxiliary groups is conducive to the transformation and absorption of VK3 in organisms. |
efficacy | MNB not only has higher stability and biological activity than MSB, but also can reduce the amount of nicotinamide added in compound feed. This product is involved in the synthesis of thrombin in the liver of animals and has a unique hemostatic effect. At the same time, it can also prevent livestock and poultry from weak physique and subcutaneous hemorrhage. The application of this product before and after the beak of wrinkled chicken can reduce bleeding, accelerate wound healing and accelerate growth. This product can be used with sulfonamides to reduce or avoid its toxic reactions; it can be used with anti-coccidia, pullorum and avian cholera drugs to enhance its preventive effect. When there are stress factors, the application of this product can relieve or eliminate the stress state and improve the feeding effect. |
use | participates in the synthesis of thrombin in animals, promotes the formation of prothrombin, and has unique hemostatic function; it can effectively prevent livestock and poultry from weak physique, subcutaneous and visceral bleeding; It can promote the growth and development of livestock and poultry and accelerate the mineralization of bones; Participate in the formation of poultry embryos to ensure the survival rate of young chicks. As an indispensable nutrient element for livestock and poultry life activities, it is a necessary addition to animal feed. Compared with MSB, MSBC and MPB, MNB has higher stability and biological activity. And it has the dual effects of vitamin K3 and nicotinamide, giving it higher economy. Its dissolution rate and solubility in water are far lower than MSB, and it is more suitable for aquatic feed. |
production method | stable vitamin K3(MNB) was synthesized from sodium bisulfite menadione (MSB) and nicotinamide at room temperature. The factors affecting the reaction were investigated. The optimized reaction conditions were as follows: n(MSB):n (nicotinamide) = 1:1.5,m(MSB):m(H2O)= 1:4, reaction time 2h,MNB yield greater than 96%, mass fraction greater than 94%, and experimental verification showed that MNB has better stability than MSB. |