2-PHENYLPYRIDINE-5-BORONIC ACID

2-PHENYLPYRIDINE-5-BORONIC ACID - Names and Identifiers

Name	2-PHENYLPYRIDINE-5-BORONIC ACID
Synonyms	5-Borono-2-phenylpyridine 2-phenylpyridin-5-ylboric acid 6-PHENYLPYRIDINE-3-BORONIC ACID 2-PHENYLPYRIDINE-5-BORONIC ACID (6-PHENYLPYRIDIN-3-YL)BORONIC ACID 2-PHENYL-5-PYRIDINYL-5-BORONIC ACID Boronic acid, B-(6-phenyl-3-pyridinyl)-
CAS	155079-10-0
InChI	InChI=1/C11H10BNO2/c14-12(15)10-6-7-11(13-8-10)9-4-2-1-3-5-9/h1-8,14-15H

2-PHENYLPYRIDINE-5-BORONIC ACID - Physico-chemical Properties

Molecular Formula	C11H10BNO2
Molar Mass	199.01
Density	1.24g/cm³
Boling Point	401.1°C at 760 mmHg
Flash Point	196.4°C
Vapor Presure	3.73E-07mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.614

2-PHENYLPYRIDINE-5-BORONIC ACID - Introduction

2-PHENYLPYRIDINE-5-BORONIC ACID, chemical formula C13H10BN, is an organic compound containing boron. It has the following properties:

1. Appearance: 2-PHENYLPYRIDINE-5-BORONIC ACID is a light yellow or brown solid.

2. Solubility: It is soluble in organic solvents, such as ethanol, dimethyl sulfoxide and chloroform, but it is difficult to dissolve in water.

3. Stability: The compound is stable and not easy to decompose.

2-PHENYLPYRIDINE-5-BORONIC ACID has the following uses:

1. Organic Synthesis: 2-PHENYLPYRIDINE-5-BORONIC ACID is commonly used as a source of boron in organic synthesis reactions. It can participate in Suzuki-Miyaura cross-coupling reactions and can react with organic halides or azo compounds to form bonded organic compounds.

2. Coordination Chemistry: it also has application value in coordination chemistry. Due to the special properties of the boron atom, 2-PHENYLPYRIDINE-5-BORONIC ACID can form complexes with specific structures and properties.

3. As a drug intermediate: The compound also has certain applications in drug research and synthesis.

The methods for preparing 2-PHENYLPYRIDINE-5-BORONIC ACID mainly include the following:

1. Barbatolo reaction: Through the Barbatolo reaction, 3-pyridinecarboxaldehyde and Phenylboronic ACID react under alkaline conditions to generate 2-PHENYLPYRIDINE-5-BORONIC ACID.

2. Reaction of a Pyridine Compound and a Boron Compound: It can be prepared by reacting a pyridine compound with a boron compound under appropriate conditions.

Safety Information:

1. 2-PHENYLPYRIDINE-5-BORONIC ACID is a general organic compound with certain toxicity. Inhalation, intake and contact with skin should be avoided.

2. Wear appropriate personal protective equipment such as gloves, glasses and lab coats when operating.

3. Should be operated in a well-ventilated place to avoid inhalation of its vapor.

4. Please read the relevant safety operation manual before use, and strictly follow the operating procedures.

Last Update：2024-04-09 21:04:16