2-Piperazineacetic acid, 3-oxo-, propyl ester
Propyl 2-(3-oxo-2-piperazinyl)acetate
CAS: 90770-36-8
Molecular Formula: C9H16N2O3
2-Piperazineacetic acid, 3-oxo-, propyl ester - Names and Identifiers
2-Piperazineacetic acid, 3-oxo-, propyl ester - Physico-chemical Properties
| Molecular Formula | C9H16N2O3 |
| Molar Mass | 200.23 |
| Density | 1.078±0.06 g/cm3(Predicted) |
| Melting Point | 85-86 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| Boling Point | 370.4±27.0 °C(Predicted) |
| pKa | 15.03±0.40(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD03444388 |
2-Piperazineacetic acid, 3-oxo-, propyl ester - Introduction
Propyl 2-(3-oxo-2-piperazinyl)acetate (new pharmaceutical reference Propyl 2-(3-oxo-2-piperazinyl)acetate) is a compound also known as pentyl 2-(3-oxo-2-piperazinyl)acetate. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: Colorless or white crystalline solid;
-Molecular formula: C12H19N3O3;
-Molecular weight: 253.30g/mol;
-Melting point: 85-90°C;
-Solubility: Soluble in alcohols, esters and ketones;
-Stability: The compound is stable under dry conditions, but it is easy to hydrolyze when exposed to water.
Use:
- Propyl 2-(3-oxo-2-piperazinyl)acetate is mainly used as a synthetic intermediate in the pharmaceutical field, especially in the research and development of new drugs, it is often used to synthesize biologically active compounds.
Preparation Method:
The preparation of-Propyl 2-(3-oxo-2-piperazinyl)acetate can be carried out by the following steps:
1.2-piperazinone reacts with Propyl amino acid salt to generate Propyl 2-(2-piperazinyl)acetate;
2. The Propyl 2-(2-piperazinyl)acetate is reacted with an acid catalyst, and heated to form the Propyl 2-(3-oxo-2-piperazinyl)acetate.
Safety Information:
-The toxicity and harmfulness data of Propyl 2-(3-oxo-2-piperazinyl)acetate are currently less reported;
-As a chemical, it should follow relevant safe operation methods and store it in a dry, low-temperature, well-ventilated place;
-When conducting experimental operations, you should wear appropriate protective equipment to avoid contact with skin and eyes to avoid adverse reactions.
Please note that the above information is for reference only, and the specific situation needs to be evaluated and implemented according to specific experimental conditions and safe operation requirements.
Nature:
-Appearance: Colorless or white crystalline solid;
-Molecular formula: C12H19N3O3;
-Molecular weight: 253.30g/mol;
-Melting point: 85-90°C;
-Solubility: Soluble in alcohols, esters and ketones;
-Stability: The compound is stable under dry conditions, but it is easy to hydrolyze when exposed to water.
Use:
- Propyl 2-(3-oxo-2-piperazinyl)acetate is mainly used as a synthetic intermediate in the pharmaceutical field, especially in the research and development of new drugs, it is often used to synthesize biologically active compounds.
Preparation Method:
The preparation of-Propyl 2-(3-oxo-2-piperazinyl)acetate can be carried out by the following steps:
1.2-piperazinone reacts with Propyl amino acid salt to generate Propyl 2-(2-piperazinyl)acetate;
2. The Propyl 2-(2-piperazinyl)acetate is reacted with an acid catalyst, and heated to form the Propyl 2-(3-oxo-2-piperazinyl)acetate.
Safety Information:
-The toxicity and harmfulness data of Propyl 2-(3-oxo-2-piperazinyl)acetate are currently less reported;
-As a chemical, it should follow relevant safe operation methods and store it in a dry, low-temperature, well-ventilated place;
-When conducting experimental operations, you should wear appropriate protective equipment to avoid contact with skin and eyes to avoid adverse reactions.
Please note that the above information is for reference only, and the specific situation needs to be evaluated and implemented according to specific experimental conditions and safe operation requirements.
Last Update：2024-04-09 15:18:10
