2-PyridineMethanol, alpha-(4-chlorophenyl)-
α-(4-chlorophenyl)pyridine-2-methanol
CAS: 27652-89-7
Molecular Formula: C12H10ClNO
2-PyridineMethanol, alpha-(4-chlorophenyl)- - Names and Identifiers
2-PyridineMethanol, alpha-(4-chlorophenyl)- - Physico-chemical Properties
| Molecular Formula | C12H10ClNO |
| Molar Mass | 219.67 |
| Density | 1.275±0.06 g/cm3(Predicted) |
| Melting Point | 78-80?C |
| Boling Point | 364.3±32.0 °C(Predicted) |
| Flash Point | 174.1°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 6.01E-06mmHg at 25°C |
| Appearance | Light brown solid |
| Color | Off-White to Grey |
| pKa | 12.46±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.614 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
2-PyridineMethanol, alpha-(4-chlorophenyl)- - Risk and Safety
| HS Code | 2933399090 |
2-PyridineMethanol, alpha-(4-chlorophenyl)- - Introduction
Α-(4-chlorophenyl)pyridine-2-methanol is an organic compound with the chemical formula C12H10ClNO. It has a-OH group on one benzene ring and a chlorine atom on the other benzene ring.
Some of the properties of this compound include:
-Appearance: Colorless to light yellow crystal or powder
-Solubility: Soluble in alcohol, ether and chloroform, slightly soluble in water
-Melting point: About 70-74 degrees Celsius
-Stability: relatively stable at room temperature, avoid contact with oxidants
α-(4-chlorophenyl)pyridine-2-methanol are mainly used as catalysts, ligands or reagents in organic synthesis reactions. It is commonly used in the synthesis of hormone compounds, bioactive molecules, as well as anti-tumor and antibacterial agents.
There are many methods for preparing the compound. A commonly used preparation method is to react the electrophilic p-nitrobenzene elicitor with 4-chlorophenylboronic acid in the presence of sodium hydride, then, the obtained intermediate is subjected to a reduction reaction to obtain the target product.
Regarding safety information, α-(4-chlorophenyl)pyridine-2-methanol may have some acute toxicity and irritation. Wear appropriate protective equipment such as lab gloves, goggles, and lab coats during handling and use. Avoid contact with skin and inhalation of dust. In case of skin contact or inhalation, rinse immediately with water and seek medical help. In addition, the compound should be used in a well-ventilated environment and away from open flames and heat sources.
Some of the properties of this compound include:
-Appearance: Colorless to light yellow crystal or powder
-Solubility: Soluble in alcohol, ether and chloroform, slightly soluble in water
-Melting point: About 70-74 degrees Celsius
-Stability: relatively stable at room temperature, avoid contact with oxidants
α-(4-chlorophenyl)pyridine-2-methanol are mainly used as catalysts, ligands or reagents in organic synthesis reactions. It is commonly used in the synthesis of hormone compounds, bioactive molecules, as well as anti-tumor and antibacterial agents.
There are many methods for preparing the compound. A commonly used preparation method is to react the electrophilic p-nitrobenzene elicitor with 4-chlorophenylboronic acid in the presence of sodium hydride, then, the obtained intermediate is subjected to a reduction reaction to obtain the target product.
Regarding safety information, α-(4-chlorophenyl)pyridine-2-methanol may have some acute toxicity and irritation. Wear appropriate protective equipment such as lab gloves, goggles, and lab coats during handling and use. Avoid contact with skin and inhalation of dust. In case of skin contact or inhalation, rinse immediately with water and seek medical help. In addition, the compound should be used in a well-ventilated environment and away from open flames and heat sources.
Last Update：2024-04-10 22:29:15
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