2-Pyridinecarbonyl chloride, 4-chloro-, hydrochloride

2-Pyridinecarbonyl chloride, 4-chloro-, hydrochloride - Names and Identifiers

Name	4-Chloropyridine-2-carbonyl Chloride Hydrochloride
Synonyms	4-chloropicolinoyl chloride hydrochloride 4-Chloro-2-pyridinecarbonyl Chloride Hydrochlorid 4-Chloropyridine-2-carbonyl Chloride Hydrochloride (4-Chloro-2-pyridinecarbonyl Chloride Hydrochloride) 2-Pyridinecarbonyl chloride, 4-chloro-, hydrochloride
CAS	51727-15-2
EINECS	1592732-453-0

2-Pyridinecarbonyl chloride, 4-chloro-, hydrochloride - Physico-chemical Properties

Molecular Formula	C6H4Cl3NO
Molar Mass	212.46
Melting Point	135-137°C (dec.)
Storage Condition	-20°C Freezer, Under Inert Atmosphere

2-Pyridinecarbonyl chloride, 4-chloro-, hydrochloride - Introduction

The Chloride Hydrochloride is an organic compound with the chemical formula C6H4Cl2NClH. The following is an introduction to its nature, use, preparation and safety information:

1. nature:
-Appearance: colorless crystalline powder
-Solubility: Soluble in chloroform, dimethyl sulfoxide and methanol, slightly soluble in ethanol and ether
-Melting point: about 130-133°C
-Density: 1.48 g/mL
-Molecular weight: 199.47g/mol

2. use: Chloride Hydrochloride is an important intermediate in organic synthesis and is often used in the synthesis of drugs and pesticides.
-It can be used to synthesize various pyridine compounds and other important intermediates in organic synthesis.

3. Preparation method:
The preparation of Chloride Hydrochloride is generally carried out by the following reactions:
-First, 4-chloropyridine and formic acid chloride are reacted to obtain 4-chloropyridine-2-carboxylic acid chloride.
-Then, the obtained 4-chloropyridine-2-carboxylic acid chloride is reacted with hydrochloric acid to obtain Chloride Hydrochloride.

4. Safety Information:
Chloride Hydrochloride is an organochlorine compound, which is irritating and corrosive. So in the use and operation need to pay attention to the following matters:
-Avoid direct contact with skin and eyes and use personal protective equipment.
-Operate in a well-ventilated place to avoid inhaling its vapors and powders.
-It should be sealed when stored, away from high temperature and fire sources.
-Collision and friction may cause fire and should be avoided.
-Follow proper laboratory procedures during processing.

Last Update：2024-04-09 21:04:16