2-Pyridinecarboxamide, 3-amino-6-chloro-

2-Pyridinecarboxamide, 3-amino-6-chloro- - Names and Identifiers

Name	6-Chloro-3-aminopyridine-2-carboxamide
Synonyms	3-amino-6-chloropicolinamide [3-AMINO-6-CHLOROPICOLIMIDE] 3-aMino-6-chloropyridine-2-carboxaMide 6-Chloro-3-aminopyridine-2-carboxamide 3-amino-6-chloropyridine-2-carboxamide 2-Pyridinecarboxamide, 3-amino-6-chloro- 3-AMino-6-chloro-pyridine-2-carboxylic acid aMide
CAS	175358-01-7
EINECS	829-520-3
InChI	InChI=1/C6H6ClN3O/c7-4-2-1-3(8)5(10-4)6(9)11/h1-2H,8H2,(H2,9,11)

2-Pyridinecarboxamide, 3-amino-6-chloro- - Physico-chemical Properties

Molecular Formula	C6H6ClN3O
Molar Mass	171.58
Density	1.484±0.06 g/cm3(Predicted)
Boling Point	349.3±42.0 °C(Predicted)
Flash Point	165.053°C
Vapor Presure	0mmHg at 25°C
pKa	14.26±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.655

2-Pyridinecarboxamide, 3-amino-6-chloro- - Introduction

The chemical formula C7H7ClN2O is an organic compound.

Nature:
It is a solid with a white to light yellow appearance. It is soluble in water and in organic solvents such as alcohols and ethers.

Use:
It is often used in the synthesis of organic compounds such as pesticides, pharmaceuticals and dyes. It is an important intermediate that can be used in the synthesis of various organic compounds.

Method:
A common preparation method is to react 3-aminopyridine with 6-chloropyridine-2-carboxylic acid. First, 3-aminopyridine is dissolved in an acidic solution, then thionyl chloride or phosphorus chloride is added as a catalyst, and finally 6-chloropyridine-2-carboxylic acid is added for reaction. After completion of the reaction, the target product is obtained by a method such as crystallization or extraction.

Safety Information:
It is relatively stable under general conditions, but contact with strong oxidants should be avoided. During operation, it is necessary to wear appropriate protective measures, such as laboratory gloves, protective glasses and laboratory coats, to prevent skin and eye contact. Proper laboratory practices and safe operating procedures should be followed during use or storage. In case of misuse, inhalation or skin contact, seek medical attention immediately.

Last Update：2024-04-09 21:01:54