2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester

2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester - Names and Identifiers

Name	6-Acetylpyridine-2-carboxylic acid ethyl ester
Synonyms	ethyl 6-acetylpicolinate 6-Acetyl-Picolinic Acid Ethyl Ester 6-ACETYL-PICOLINIC ACID ETHYL ESTER ethyl 6-acetylpyridine-2-carboxylate Ethyl 6-acetyl-2-pyridinecarboxylate 6-Acetylpyridine-2-carboxylic acid ethyl ester 2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester
CAS	114578-70-0
InChI	InChI=1/C10H11NO3/c1-3-14-10(13)9-6-4-5-8(11-9)7(2)12/h4-6H,3H2,1-2H3

2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester - Physico-chemical Properties

Molecular Formula	C10H11NO3
Molar Mass	193.2
Density	1.145±0.06 g/cm3(Predicted)
Melting Point	50.0-51.5 °C
Boling Point	329.6±27.0 °C(Predicted)
Flash Point	153.146°C
Solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to Off-White
pKa	0.97±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.514
Use	This product is for scientific research only and shall not be used for other purposes.

2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester - Risk and Safety

Hazard Class

IRRITANT

2-Pyridinecarboxylic acid, 6-acetyl-, ethyl ester - Introduction

Ethyl 6-acetylpyridine-2-carboxylate, also known as acetylpyridine, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Ethyl 6-acetylpyridine-2-carboxylate is a colorless liquid.
-Solubility: Soluble in organic solvents such as ether and chloroform, insoluble in water.

Use:
-6-acetylpyridine-2-carboxylic acid ethyl ester can be used as an intermediate in organic synthesis.
-It is often used as a raw material in the field of medicine and pesticides, and plays a specific role in the synthesis of certain drugs.

Method:
-6-acetylpyridine-2-carboxylic acid ethyl ester can be synthesized by acetylation reaction. A common synthesis method is the reaction of 2-carboxylic acid pyridine and ethanol in the presence of acetic anhydride (Ac2O), and after appropriate reaction conditions and procedures, 6-acetylpyridine-2-carboxylic acid ethyl ester is obtained.

Safety Information:
-6-acetylpyridine-2-carboxylic acid ethyl ester in use should pay attention to protection, avoid contact with skin and eyes.
-During industrial production and laboratory operations, appropriate ventilation and personal protective measures are required, such as wearing chemical protective gloves and goggles.
-The storage and handling of this compound should comply with relevant regulations and safe operating procedures, and be placed in a dry, cool, well-ventilated place.

Last Update：2024-04-09 02:00:41