2-Pyridineethanol, b,b-difluoro-

2-Pyridineethanol, b,b-difluoro- - Names and Identifiers

Name	2,2-DIFLUORO-2-PYRIDIN-2-YLETHANOL
Synonyms	2-Pyridineethanol, b,b-difluoro- 2-Pyridineethanol, β,β-difluoro- 2,2-Difluoro-2-(2-pyridyl)ethanol 2,2-DIFLUORO-2-PYRIDIN-2-YLETHANOL 2,2-difluoro-2-(2-pyridinyl)ethanol 2,2-Difluoro-2-(2-pyridyl)ethan-1-ol 2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol
CAS	267875-65-0

2-Pyridineethanol, b,b-difluoro- - Physico-chemical Properties

Molecular Formula	C7H7F2NO
Molar Mass	159.1333864
Density	1.275
Boling Point	255℃
Flash Point	108℃
pKa	13.31±0.10(Predicted)
Storage Condition	Room Temprature

2-Pyridineethanol, b,b-difluoro- - Introduction

It is an organic compound whose chemical formula is C7H6F2NO. The following describes the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless liquid
-Melting point:-17 ° C
-Boiling point: 144-145 ° C
-Density: 1.234 g/mL
-Solubility: Soluble in water and most organic solvents

Use:
2. It has a wide range of applications in the chemical and pharmaceutical industries, mainly for the following:
-As a synthesis intermediate: It can be used to synthesize other organic compounds, such as compounds containing difluorinated hydrocarbon groups and pyridyl groups.
-As a solvent: Due to its good solubility, it is often used as a solvent in chemical experiments.
-Used in pharmacy: The compound is used as an intermediate or reagent in the pharmaceutical field for the preparation of drugs.

Method:
2. It can be prepared by the following methods:
1. Reacting 2-aminopyridine with 1,1,2,2-tetrafluoroethylene to obtain 3,3, 4,4-tetrafluoro-1-pyridylacrylic acid.
2. Reduction of 3,3, 4,4-tetrafluoro-1-pyridyl acrylic acid to 3,3, 4,4-tetrafluoro-1-pyridyl ethanol.
3.3,3,4, 4-tetrafluoro-1-pyridyl ethanol reacts with hydrogen chloride to generate 2, br.

Safety Information:
- 2, Irritant and may cause eye, skin and respiratory tract irritation.
-Wear protective gloves and goggles when using, and make sure to operate in a well-ventilated area.
-Avoid contact with strong oxidants and other substances during storage, and keep the container closed and stored in a cool and dry place.
-When handling the compound, follow the correct laboratory operating procedures and strictly follow the safety operating guidelines.

Last Update：2024-04-09 21:04:16