2-Pyridinesulfonyl chloride, 5-(trifluoromethyl)-

2-Pyridinesulfonyl chloride, 5-(trifluoromethyl)- - Names and Identifiers

Name	5-(Trifluoromethyl)pyridine-2-sulfonyl chloride
Synonyms	5-TRIFLUOROMETHYL-2- 5-TRIFLUOROMETHYL-2-PYRIDINESULFONYL CHLORIDE 5-(Trifluoromethyl)pyridine-2-sulfonyl Chloride 5-(Trifluoromethyl)-2-pyridinesulfonyl chloride 5-(Trifluoromethyl)pyridine-2-sulfonyl chloride 5-trifluoromethyl-pyridin-2-ylsulfonyl chloride 2-pyridinesulfonyl chloride, 5-(trifluoromethyl)- 2-Pyridinesulfonyl chloride, 5-(trifluoromethyl)- 5-Trifluoromethyl-2-pyridinesulfonyl ChlorideDiscontinued See T791526 5-Trifluoromethyl-2-pyridinesulfonyl Chloride Discontinued. Pleases see T791526
CAS	174485-72-4
EINECS	200-258-5
InChI	InChI=1/C6H3ClF3NO2S/c7-14(12,13)5-2-1-4(3-11-5)6(8,9)10/h1-3H

2-Pyridinesulfonyl chloride, 5-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C6H3ClF3NO2S
Molar Mass	245.61
Density	1.607g/cm³
Melting Point	50-52°C
Boling Point	277.683°C at 760 mmHg
Flash Point	121.738°C
Solubility	Chloroform, Dichloromethane
Vapor Presure	0.008mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Stability	Temperature and Moisture Sensitive
Refractive Index	1.477

2-Pyridinesulfonyl chloride, 5-(trifluoromethyl)- - Introduction

5-(Trifluoromethyl)pyridine-2-sulfonyl chloride, also known as TFPSCl, is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: TFPSCl is a colorless to light yellow liquid.
-Solubility: TFPSCl is soluble in organic solvents such as chloroform, dimethyl sulfoxide, ethanol and the like.

Use:
- TFPSCl is commonly used as a reagent in chemical synthesis, especially in pharmaceutical synthesis and organic synthesis.
-It can be used for sulfonylation reaction and carboxylic acid activation reaction.
- TFPSCl is also used to prepare some organic photosensitive compounds and polymers.

Method:
The preparation of-TFPSCl is usually prepared by reacting 3-trifluoromethylpyridine with sulfonyl chloride.
-The reaction is carried out under inert gas to ensure that there is no moisture during the reaction.
-After the reaction, the product can be purified by distillation or other purification methods.

Safety Information:
-The use of TFPSCl requires attention to safety, because it is an organochlorine compound.
-Wear protective gloves, goggles and protective clothing during operation.
-Avoid breathing gas, contact with skin and eyes.
-Store TFPSCl in a dry, cool place, and avoid contact with water and humid air.

Please note that TFPSCl is a chemical reagent. Please read the relevant safety manual and material safety data sheet carefully before use, and operate in strict accordance with the operating procedures.

Last Update：2024-04-09 19:05:47