2-Thiophenecarbonyl chloride, 5-chloro- (9CI)
5-Chlorothiophene-2-carbonyl chloride
CAS: 42518-98-9
Molecular Formula: C5H2Cl2OS
2-Thiophenecarbonyl chloride, 5-chloro- (9CI) - Names and Identifiers
2-Thiophenecarbonyl chloride, 5-chloro- (9CI) - Physico-chemical Properties
| Molecular Formula | C5H2Cl2OS |
| Molar Mass | 181.04 |
| Density | 1.50 |
| Melting Point | 4℃ |
| Boling Point | 122-127℃/16Torr |
| Flash Point | 89.2°C |
| Water Solubility | Slightly soluble in water. |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.0937mmHg at 25°C |
| Appearance | Oil |
| Color | Colourless to Pale Yellow |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Stability | Hygroscopic |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.6040 to 1.6080 |
2-Thiophenecarbonyl chloride, 5-chloro- (9CI) - Risk and Safety
| Risk Codes | R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 3265 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
| Packing Group | Ⅲ |
2-Thiophenecarbonyl chloride, 5-chloro- (9CI) - Reference Information
| introduction | the melting point of 5-chlorothiophene-2-formyl chloride is 44 ℃, the boiling point is 122-127 ℃/16Torr, the density is 1.50, and the refractive index is 1.6040-1.6080. It is a chemical intermediate, which is often used in organic synthesis, small molecule synthesis of drugs and other chemical fields. |
| use | 5-chlorothiophene-2-formyl chloride is mainly used as an intermediate in drug synthesis. due to the special activity of thiophene structure, it plays an important role in the development of new drugs. According to the existing literature, 5-chlorothiophene-2-formyl chloride may play an important role in the synthesis of tens of thousands of drugs such as anthelmintic drugs, anti-AIDS poisons, anti-hepatitis B virus and anti-cold drugs, anti-rheumatic drugs, antihistamines, anti-diabetic drugs and anti-cancer drugs. |
Last Update：2024-04-09 02:00:05
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