2-aMino-4,6-diMethoxybenzaMide - Names and Identifiers
2-aMino-4,6-diMethoxybenzaMide - Physico-chemical Properties
Molecular Formula | C9H12N2O3
|
Molar Mass | 196.2 |
Density | 1.238±0.06 g/cm3(Predicted) |
Boling Point | 331.6±42.0 °C(Predicted) |
pKa | 15.70±0.50(Predicted) |
Storage Condition | 2-8°C(protect from light) |
2-aMino-4,6-diMethoxybenzaMide - Introduction
Benzamide, 2-amino-4,6-dimethoxy-, often abbreviated as 2-ADMBA, is an organic compound. The following is a description of the nature, use, preparation and safety information of 2-ADMBA:
Nature:
-Appearance: 2-ADMBA is a white or brownish yellow crystalline solid.
-Solubility: Its solubility in water is relatively low, but it has good solubility in organic solvents.
-Chemical structure: Its chemical structure contains a benzene ring with an acyl group, an amino group, and two methoxy groups.
Use:
- 2-ADMBA is widely used in organic synthesis, especially for the synthesis of many other compounds.
-It can be used as a reagent in organic synthesis, for example as a reagent or catalyst in acylation reactions.
- 2-ADMBA can also be used as an intermediate to participate in drug synthesis.
Preparation Method:
-Generally, 2-ADMBA is prepared by reacting p-dimethylaminobenzoic acid with bromomethyl ether.
-First, p-dimethylaminobenzoic acid and phosphorous acid are esterified to prepare p-dimethoxybenzoic acid.
-Then, p-dimethoxybenzoic acid is reacted with phosphoric acid, phosphorus trichloride, etc. to form 2-ADMBA.
Safety Information:
2-ADMBA is generally considered to be a relatively safe compound.
-However, it is still necessary to pay attention to protective measures during operation, such as wearing appropriate protective glasses and gloves.
-Avoid inhalation or contact with skin and eyes. In use or operation should follow the relevant safety procedures.
-In case of ingestion or other accidents, seek medical advice immediately and consult a professional.
Last Update:2024-04-09 21:01:54