2-acetylaminopyridine
2-Acetamidopyridine
CAS: 5231-96-9
Molecular Formula: C7H8N2O
2-acetylaminopyridine - Names and Identifiers
| Name | 2-Acetamidopyridine |
| Synonyms | AKOS AU36-M356 2-Acetamidopyridine 2-ACETAMIDOPYRIDINE n-2-pyridyl-acetamid 2-acetylaminopyridine N-(2-PYRIDYL)ACETAMIDE n-2-pyridinyl-acetamid N-[2-pyridyl]acetamide N-pyridin-2-ylacetamide N-(2-PYRIDINYL)ACETAMIDE N-(Pyridine-2-yl)acetamide |
| CAS | 5231-96-9 |
| EINECS | 214-589-6 |
| InChI | InChI=1/C7H8N2O/c1-6(10)9-7-4-2-3-5-8-7/h2-5H,1H3,(H,8,9,10) |
2-acetylaminopyridine - Physico-chemical Properties
| Molecular Formula | C7H8N2O |
| Molar Mass | 136.15 |
| Density | 1.176±0.06 g/cm3(Predicted) |
| Melting Point | 69 °C |
| Boling Point | 148 °C / 13mmHg |
| Flash Point | 162°C |
| Vapor Presure | 6.64E-05mmHg at 25°C |
| pKa | 13.82±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.581 |
2-acetylaminopyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| RTECS | AC7859000 |
2-acetylaminopyridine - Introduction
2-Acetamidopyridine is an organic compound with the chemical formula C7H8N2O. The following is a description of the properties, uses, formulation and safety information of 2-Acetamidopyridine:
Nature:
-Appearance: 2-Acetamidopyridine is a colorless crystal or white crystalline powder.
-Solubility: It can be dissolved in some organic solvents such as ethanol, chloroform and ether, but the solubility in water is relatively poor.
-Melting point: Its melting point is about 80-83°C.
Use:
-Industrial use: 2-Acetamidopyridine is an important intermediate compound, which is widely used in organic synthesis and is often used in the synthesis of drugs, dyes and pesticides.
-Medical use: It also has some applications in the medical field, such as as raw materials or intermediates for certain drugs.
Preparation Method:
The synthesis of-2-Acetamidopyridine can be carried out by an acetylation reaction. The specific step is to react 2-aminopyridine with acetic anhydride (acetic anhydride) in the presence of a suitable catalyst to form 2-Acetamidopyridine.
Safety Information:
- 2-Acetamidopyridine has low toxicity, but it is still necessary to pay attention to safe operation. Avoid direct contact with skin and eyes, and make sure to operate in a well-ventilated area. When using and storing, please follow safe operating procedures and avoid contact with flammable substances. In case of contact or accidental inhalation, seek medical attention immediately.
Nature:
-Appearance: 2-Acetamidopyridine is a colorless crystal or white crystalline powder.
-Solubility: It can be dissolved in some organic solvents such as ethanol, chloroform and ether, but the solubility in water is relatively poor.
-Melting point: Its melting point is about 80-83°C.
Use:
-Industrial use: 2-Acetamidopyridine is an important intermediate compound, which is widely used in organic synthesis and is often used in the synthesis of drugs, dyes and pesticides.
-Medical use: It also has some applications in the medical field, such as as raw materials or intermediates for certain drugs.
Preparation Method:
The synthesis of-2-Acetamidopyridine can be carried out by an acetylation reaction. The specific step is to react 2-aminopyridine with acetic anhydride (acetic anhydride) in the presence of a suitable catalyst to form 2-Acetamidopyridine.
Safety Information:
- 2-Acetamidopyridine has low toxicity, but it is still necessary to pay attention to safe operation. Avoid direct contact with skin and eyes, and make sure to operate in a well-ventilated area. When using and storing, please follow safe operating procedures and avoid contact with flammable substances. In case of contact or accidental inhalation, seek medical attention immediately.
Last Update：2024-04-09 19:05:50
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