2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid

2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid - Names and Identifiers

Name	2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid
Synonyms	AM-TOB Einecs 257-650-5 5-AMINOMETHYLTOBIAS ACID 2-Amino-5-aminomethylnaphthalin-1-sulfonsure 2-Amino-5-(aminomethyl)-1-naphthalenesulfonic acid 2-amino-5-(aminomethyl)naphthalene-1-sulfonic acid 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid 2-Amino-5-(aminomethyl)naphthalene-1-sulphonic acid 2-Amino-5-(aminomethyl)-naphthalene-1-sulfonic acid 1-Naphthalenesulfonic acid, 2-amino-5-(aminomethyl)-
CAS	52084-84-1
EINECS	257-650-5
InChI	InChI=1/C11H12N2O3S/c12-6-7-2-1-3-9-8(7)4-5-10(13)11(9)17(14,15)16/h1-5H,6,12-13H2,(H,14,15,16)

2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid - Physico-chemical Properties

Molecular Formula	C11H12N2O3S
Molar Mass	252.29
Density	1.496±0.06 g/cm3(Predicted)
pKa	-1.07±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.719

2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid - Introduction

2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid is an organic compound with the chemical formula C11H12N2O3S. It is a white crystalline powder, soluble in water and alcohol solvents. The following is an introduction to the nature, use, preparation and safety information of 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid:

Nature:
-Appearance: White crystalline powder
-Molecular weight: 260.3g/mol
-Melting Point: 284-289°C
-Solubility: Soluble in water and alcohol solvents

Use:
-as a chemical reagent: 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid is often used as a chemical analysis reagent for the detection of metal ions and the synthesis of fluorescent dyes.
-as a fluorescent dye: due to its molecular structure contains aromatic rings and amine groups, 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid can be used to label and detect biological molecules, proteins and cells.

Preparation Method:
2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid can be prepared by two methods:
1. p-Nitroaniline reacts with formaldehyde to generate 5-aminomethyl -1,8-dinitronaphthalene. This compound is then reacted with sulfurous acid to produce 5-aminomethyl-1, 8-dinitronaphthalene sulfinate. Finally, it was converted to 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid by reduction.
2. by the reaction of nitrosyl chloride and 2-amino naphthalene, 2-nitroso-5-aminomethylnaphthalene is generated. This compound is then reacted with formaldehyde to produce 5-aminomethyl-2-nitrosonaphthalene. Finally, 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid was formed by reaction of sodium sulfite with this compound.

Safety Information:
- 2-amino-5-(aminomethyl) Exposure to naphthalene-1-sulphonic acid may be harmful to human health, such as skin irritation and eye irritation.
-Personal protective equipment such as protective gloves and goggles are required for use and operation.
-Avoid inhaling dust and avoid contact with skin and eyes.
-If inhaled or exposed to this compound, immediately flush the affected area with plenty of water and seek medical help.
-Please store and handle 2-amino-5-(aminomethyl)naphthalene-1-sulphonic acid properly and avoid contact with oxidizing agents and strong acids.

Last Update：2024-04-10 22:29:15