2-formamidophenylboronic acid pinacol ester
N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide
CAS: 480425-36-3
Molecular Formula: C13H18BNO3
2-formamidophenylboronic acid pinacol ester - Names and Identifiers
2-formamidophenylboronic acid pinacol ester - Physico-chemical Properties
| Molecular Formula | C13H18BNO3 |
| Molar Mass | 247.1 |
| Density | 1.09±0.1 g/cm3(Predicted) |
| Melting Point | 85-89°C(lit.) |
| Boling Point | 412.2±28.0 °C(Predicted) |
| Flash Point | 203.1°C |
| Vapor Presure | 5.26E-07mmHg at 25°C |
| pKa | 15.14±0.70(Predicted) |
| Refractive Index | 1.514 |
2-formamidophenylboronic acid pinacol ester - Risk and Safety
| WGK Germany | 3 |
2-formamidophenylboronic acid pinacol ester - Introduction
N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide is an organic compound with the chemical formula C14H18BNO3. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: Colorless or yellowish liquid.
-Melting point: about 30-40°C.
-Boiling point: about 290-295°C.
-Density: about 1.124 g/mL.
-Solubility: Soluble in some organic solvents, such as ether and chloroform.
2. use:
-As a reagent in organic synthesis, used to synthesize other organic compounds.
-In pharmaceutical research, it is used to synthesize pharmaceutical intermediates.
-Material synthesis for organic light-emitting diodes (OLED).
3. Preparation method:
The preparation of N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide is generally carried out by the following steps:
-First, 4,4,5,5-tetramethyl -1,3, 2-dioxaborolane (CAS No.: 149239-70-9) is reacted with benzamide to generate benzene hexahydro -2-boron -1,3, 5-trioxepanediane -4-one.
-Subsequently, reaction with ethyl chloroformate gives the target product N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide.
4. Safety Information:
- N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide has limited toxicity information and requires caution when used.
-Avoid contact with skin, eyes and respiratory tract.
-During use, it is recommended to wear appropriate personal protective equipment, such as gloves and goggles, and ensure that the operation is carried out in a well-ventilated place.
-Follow relevant chemical safety practices during handling and storage.
1. nature:
-Appearance: Colorless or yellowish liquid.
-Melting point: about 30-40°C.
-Boiling point: about 290-295°C.
-Density: about 1.124 g/mL.
-Solubility: Soluble in some organic solvents, such as ether and chloroform.
2. use:
-As a reagent in organic synthesis, used to synthesize other organic compounds.
-In pharmaceutical research, it is used to synthesize pharmaceutical intermediates.
-Material synthesis for organic light-emitting diodes (OLED).
3. Preparation method:
The preparation of N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide is generally carried out by the following steps:
-First, 4,4,5,5-tetramethyl -1,3, 2-dioxaborolane (CAS No.: 149239-70-9) is reacted with benzamide to generate benzene hexahydro -2-boron -1,3, 5-trioxepanediane -4-one.
-Subsequently, reaction with ethyl chloroformate gives the target product N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide.
4. Safety Information:
- N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide has limited toxicity information and requires caution when used.
-Avoid contact with skin, eyes and respiratory tract.
-During use, it is recommended to wear appropriate personal protective equipment, such as gloves and goggles, and ensure that the operation is carried out in a well-ventilated place.
-Follow relevant chemical safety practices during handling and storage.
Last Update：2024-04-09 21:01:54
