Name | Minocycline |
Synonyms | cl59806 minocyclin Minocycline 12,12a-tetrahydroxy-1,11-dioxo--10 7-dimethylamino-6-demethyl-6-deoxytetracycline -3,10,12,12a-tetrahydroxy-1,11,-dioxo-,(4s-(4alpha,4aalpha,5aalpha,12aalpha)) 2-naphthacenecarboxamide,4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro (2e,4s,4ar,5as,12ar)-2-(amino-hydroxy-methylidene)-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4h-tetracene-1,3,12-trione (2E,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione [4s-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride |
CAS | 10118-90-8 |
EINECS | 800-277-5 |
InChI | InChI=1/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1 |
Molecular Formula | C23H27N3O7 |
Molar Mass | 457.48 |
Density | 1.3283 (rough estimate) |
Boling Point | 563.31°C (rough estimate) |
Specific Rotation(α) | D25 -166° (c = 0.524) |
Water Solubility | 52g/L(25 ºC) |
pKa | pKa 2.8 (Uncertain);5.0 (Uncertain);7.8 (Uncertain);9.5 (Uncertain) |
Refractive Index | 1.6500 (estimate) |
Physical and Chemical Properties | Minocycline (Minocycline Hydrochloride) also known as Minocycline Hydrochloride, its Hydrochloride is yellow crystalline powder, odorless, bitter, slightly hygroscopicity, stable at room temperature, but light can be deteriorated. Soluble in water, soluble in alkali metal hydroxide or carbonate solution, when metal ions lose antibacterial activity. The pH of the 1% aqueous solution is 3.5-4.5. This information was compiled by Xiaonan. |