2-pyridinemethanol, 5-(trifluoromethyl)-

2-pyridinemethanol, 5-(trifluoromethyl)- - Names and Identifiers

Name	[5-(Trifluoromethyl)pyridin-2-yl]methanol
Synonyms	5-(trifluoromethyl)-2-Pyridinemethanol 2-Pyridinemethanol, 5-(trifluoromethyl)- 2-pyridinemethanol, 5-(trifluoromethyl)- (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL [5-(Trifluoromethyl)-2-pyridinyl]methanol [5-(Trifluoromethyl)pyridin-2-yl]methanol 2-HydroxyMethyl-5-(TrifluorMethyl)-Pyridine 2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine
CAS	31181-84-7
InChI	InChI=1/C7H6F3NO/c8-7(9,10)5-1-2-6(4-12)11-3-5/h1-3,12H,4H2

2-pyridinemethanol, 5-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C7H6F3NO
Molar Mass	177.12
Density	1.362±0.06 g/cm3(Predicted)
Boling Point	215.5±35.0 °C(Predicted)
Flash Point	84.1°C
Vapor Presure	0.0862mmHg at 25°C
pKa	13.16±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Irritant
Refractive Index	1.462
MDL	MFCD04117762

2-pyridinemethanol, 5-(trifluoromethyl)- - Risk and Safety

Hazard Class

IRRITANT

2-pyridinemethanol, 5-(trifluoromethyl)- - Introduction

[5-(Trifluoromethyl)pyridin-2-yl]methanol is an organic compound with the chemical formula C7H5F3NO. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: White or off-white solid
-Solubility: Soluble in organic solvents such as ether, methanol and dichloromethane
-Melting point: About 100-101 ° C
-Boiling point: About 238-239 ° C
-Density: 1.376g/cm³

Use:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol is a commonly used organic synthesis intermediate, which is widely used in the fields of medicine, pesticide and chemical industry.
-It is often used as a reagent and catalyst in organic synthesis reactions, especially in fluorination reactions.
-The compound can also be used to prepare other organic compounds, such as drugs and pesticides that use it as derivatives.

Method:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol can be prepared by the following reaction: 5-trifluoromethylpyridine and methanol are reacted under appropriate reaction conditions to obtain the target product.

Safety Information:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol is generally relatively safe under the correct use and storage, but the following matters still need to be paid attention:
-This compound can cause eye and skin irritation and direct contact should be avoided.
-Avoid contact with oxidants during operation or storage to prevent fire or explosion.
-During use, good ventilation measures should be taken to avoid inhalation of aerosols.
-Correct laboratory procedures and safe handling should be followed when handling the compound.

Last Update：2024-04-09 02:00:45