218609-00-8

218609-00-8 - Names and Identifiers

Name	Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid
Synonyms	RARECHEM AK PT B066 BOC-D-PHE(4-F)-(C*CH2)OH BOC-D-BETA-HOPHE(4-F)-OH BOC-4-FLUORO-D-BETA-HOMOPHENYLALANINE BOC-(R)-3-AMINO-4-(4-FLUOROPHENYL)BUTANOIC ACID BOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid N-BETA-T-BUTOXYCARBONYL-D-HOMO(4-FLUOROPHENYL)ALANINE (R)-3-TERT-BUTOXYCARBONYLAMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID
CAS	218609-00-8

218609-00-8 - Physico-chemical Properties

Molecular Formula	C15H20FNO4
Molar Mass	297.32
Density	1.192±0.06 g/cm3(Predicted)
Boling Point	449.3±40.0 °C(Predicted)
pKa	4.42±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature

218609-00-8 - Risk and Safety

Hazard Class

IRRITANT

218609-00-8 - Introduction

Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid is an organic compound with the following properties:

1. Appearance: white crystal or crystalline powder.
2. Chemical formula: C18H23FNO4.
3. Molecular weight: 333.38g/mol.
4. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).
5. Melting Point: about 100-102 ℃.

Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid is commonly used in organic synthesis reactions, especially in peptide synthesis. It is often present as a protecting group (protecting amino), which can be removed by the carbonic anhydride method.

Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid can be prepared by the following methods: the protected aminobutyric acid is reacted with 4-fluorophenylcarbaldehyde under basic conditions and then acidified with acetic anhydride to give the desired product.

Regarding safety information, Boc-(R)-3-Amino-4-(4-fluoro-phenyl)-butyric acid may have certain hazards, therefore, it is necessary to comply with relevant safety operating procedures when using. The compound may cause irritation to the eyes, skin and respiratory tract. Appropriate protective equipment such as gloves, goggles and protective masks should be worn during operation. When storing and handling the compound, care should be taken to avoid ignition and contact with oxidizing agents. It is best to operate in a well-ventilated area and avoid inhaling dust. Such as accidental contact or inhalation, should immediately seek medical attention.

Last Update：2024-04-10 22:29:15