2597-56-0
2-methoxy-4-nitrobenzoic acid
CAS: 2597-56-0
Molecular Formula: C8H7NO5
2597-56-0 - Names and Identifiers
| Name | 2-methoxy-4-nitrobenzoic acid |
| Synonyms | NSC 229300 RARECHEM AL BO 1464 4-Nitro-o-anisic acid 2-Carboxy-5-nitroanisole 2-METHOXY-4-NITROBENZOIC ACID 2-Methoxy-4-nitrobenzoid acid 4-NITRO-2-METHOXYBENZOIC ACID 2-methoxy-4-nitrobenzoic acid 2-Methoxy-4-nitrobenzaldehyde |
| CAS | 2597-56-0 |
| EINECS | 219-998-6 |
| InChI | InChI=1/C8H7NO5/c1-14-7-4-5(9(12)13)2-3-6(7)8(10)11/h2-4H,1H3,(H,10,11) |
2597-56-0 - Physico-chemical Properties
| Molecular Formula | C8H7NO5 |
| Molar Mass | 197.14 |
| Density | 1.430±0.06 g/cm3(Predicted) |
| Melting Point | 146-148 °C (lit.) |
| Boling Point | 390.9±27.0 °C(Predicted) |
| Flash Point | 190.2°C |
| Solubility | Acetic Acid, Methanol |
| Vapor Presure | 8.25E-07mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White Crystalline |
| pKa | 3.13±0.13(Predicted) |
| Refractive Index | 1.588 |
2597-56-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29189900 |
2597-56-0 - Introduction
2-methoxy-4-nitrobenzoic acid, chemical formula C8H7NO5, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-methoxy-4-nitrobenzoic acid is a pale yellow crystalline solid.
-Melting point: About 154-157 ℃.
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
-Chemical reagent: 2-methoxy-4-nitrobenzoic acid can be used as a reagent in organic synthesis.
-Drug intermediates: It can also be used as an intermediate for some drugs, such as the synthesis of certain antibacterial drugs and anti-inflammatory drugs.
Method:
The preparation of 2-methoxy-4-nitrobenzoic acid is mainly realized by the oxidation reaction of 2-methoxy-4-nitrobenzene methane. The specific preparation method may include the following steps:
1. Dissolve 2-methoxy-4-nitrophenylmethane in an appropriate solvent, such as ethanol or dichloromethane.
2. Add an appropriate amount of oxidizing agent to the solution, such as hydrogen peroxide or peracetyl peroxide. After a period of reaction, the product will form and crystallize out.
3. The resulting solid product is collected, filtered, washed and dried to give 2-methoxy-4-nitrobenzoic acid.
Safety Information:
2-methoxy-4-nitrobenzoic acid is generally relatively safe under normal use and storage conditions. However, as an organic compound, there are still some common laboratory safety measures to follow:
-Avoid inhalation: Avoid inhaling dust, gases or vapours. Wear a suitable protective mask or face screen during operation.
-Avoid Contact: Avoid contact with skin, eyes and mucous membranes. Wear appropriate protective gloves and goggles during operation.
-Storage Note: 2-methoxy-4-nitrobenzoic acid should be stored in a dry, sealed container, away from ignition and igniting objects.
In addition, the use and handling of chemicals should follow the correct laboratory procedures and follow relevant safety instructions. The safety data sheets (MSDS) of the relevant chemicals should be carefully read and understood before operation. Please note that any chemical should be used under the right conditions and with the right facilities.
Nature:
-Appearance: 2-methoxy-4-nitrobenzoic acid is a pale yellow crystalline solid.
-Melting point: About 154-157 ℃.
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
-Chemical reagent: 2-methoxy-4-nitrobenzoic acid can be used as a reagent in organic synthesis.
-Drug intermediates: It can also be used as an intermediate for some drugs, such as the synthesis of certain antibacterial drugs and anti-inflammatory drugs.
Method:
The preparation of 2-methoxy-4-nitrobenzoic acid is mainly realized by the oxidation reaction of 2-methoxy-4-nitrobenzene methane. The specific preparation method may include the following steps:
1. Dissolve 2-methoxy-4-nitrophenylmethane in an appropriate solvent, such as ethanol or dichloromethane.
2. Add an appropriate amount of oxidizing agent to the solution, such as hydrogen peroxide or peracetyl peroxide. After a period of reaction, the product will form and crystallize out.
3. The resulting solid product is collected, filtered, washed and dried to give 2-methoxy-4-nitrobenzoic acid.
Safety Information:
2-methoxy-4-nitrobenzoic acid is generally relatively safe under normal use and storage conditions. However, as an organic compound, there are still some common laboratory safety measures to follow:
-Avoid inhalation: Avoid inhaling dust, gases or vapours. Wear a suitable protective mask or face screen during operation.
-Avoid Contact: Avoid contact with skin, eyes and mucous membranes. Wear appropriate protective gloves and goggles during operation.
-Storage Note: 2-methoxy-4-nitrobenzoic acid should be stored in a dry, sealed container, away from ignition and igniting objects.
In addition, the use and handling of chemicals should follow the correct laboratory procedures and follow relevant safety instructions. The safety data sheets (MSDS) of the relevant chemicals should be carefully read and understood before operation. Please note that any chemical should be used under the right conditions and with the right facilities.
Last Update：2024-04-09 20:52:54
