28180-80-5
2,2,2-Trichloroethyl3-methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicydo[4.2.0]oct-2-ene-2-carboxylate
CAS: 28180-80-5
Molecular Formula: C18H17Cl3N2O4S
28180-80-5 - Names and Identifiers
28180-80-5 - Physico-chemical Properties
| Molecular Formula | C18H17Cl3N2O4S |
| Molar Mass | 463.76 |
| Physical and Chemical Properties | Crystallization. Melting point 125-127 ℃. |
28180-80-5 - References
| Use | an intermediate of cephalexin. |
| production method | trichloroethyl alcohol and penicillin G were esterified with phosphorus oxychloride and pyridine to produce trichloroethyl penicillate, then by peracetic acid and hydrogen peroxide oxidation, penicillanic acid trichloroethyl ester-S-oxide, the latter in ethyl acetate in pyridine and phosphoric acid in the participation of molecular rearrangement and expanding ring to produce the product. |
Last Update：2024-04-10 22:29:15
