3'-Bromo-2'-Fluoroacetophenone
3'-Bromo-2'-Fluoroacetophenone
CAS: 161957-61-5
Molecular Formula: C8H6BrFO
3'-Bromo-2'-Fluoroacetophenone - Names and Identifiers
| Name | 3'-Bromo-2'-Fluoroacetophenone |
| Synonyms | 153471 1-(3-Bromo-2-fL 3-Bromo-2-fluorobenzophenone 3'-Bromo-2'-Fluoroacetophenone 1-(3-Bromo-2-fluoro-phenyl)-ethanone Ethanone, 1-(3-bromo-2-fluorophenyl)- 1-(3-Bromo-2-fluorophenyl)ethan-1-one |
| CAS | 161957-61-5 |
| InChI | InChI=1/C8H6BrFO/c1-5(11)6-3-2-4-7(9)8(6)10/h2-4H,1H3 |
3'-Bromo-2'-Fluoroacetophenone - Physico-chemical Properties
| Molecular Formula | C8H6BrFO |
| Molar Mass | 217.04 |
| Density | 1.535±0.06 g/cm3(Predicted) |
| Boling Point | 252.4±25.0 °C(Predicted) |
| Flash Point | 106.5°C |
| Vapor Presure | 0.0194mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | 2-8°C |
| Refractive Index | 1.534 |
3'-Bromo-2'-Fluoroacetophenone - Introduction
3 '-Bromo-2'-Fluoroacetophenone is an organic compound with the chemical formula C8H6BrFO. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 3 '-Bromo-2'-Fluoroacetophenone is a colorless to pale yellow liquid.
2. Melting point: The melting point of the compound is 28-29°C.
3. Boiling point: Its boiling point is about 252-254 ℃.
4. Solubility: 3 '-Bromo-2'-Fluoroacetophenone is soluble in organic solvents such as alcohols, ethers and esters, and insoluble in water.
Use:
3 '-Bromo-2'-Fluoroacetophenone has important application value in organic synthesis, and is commonly used as fluorination reagent, catalyst and intermediate. It is commonly used in the synthesis of drugs, dyes and chemicals.
Method:
A common method for preparing 3 '-Bromo-2'-Fluoroacetophenone is obtained by reacting acetophenone with bromine and hydrogen fluoride. Acetophenone was first added to the reaction vessel, then hydrogen fluoride was gradually added, and finally bromine was gradually added. After completion of the reaction, isolation and purification of the product are carried out.
Safety Information:
1. 3 '-Bromo-2'-Fluoroacetophenone should pay attention to fire prevention and ventilation during use and storage.
2. Inhalation and contact with skin may cause irritation and respiratory problems, so appropriate protective equipment should be worn during operation.
3. If ingested or in contact with eyes, rinse immediately with plenty of water and seek medical attention.
4. Please take care to properly store and handle the compound and avoid contact with strong oxidants and flammable materials.
Nature:
1. Appearance: 3 '-Bromo-2'-Fluoroacetophenone is a colorless to pale yellow liquid.
2. Melting point: The melting point of the compound is 28-29°C.
3. Boiling point: Its boiling point is about 252-254 ℃.
4. Solubility: 3 '-Bromo-2'-Fluoroacetophenone is soluble in organic solvents such as alcohols, ethers and esters, and insoluble in water.
Use:
3 '-Bromo-2'-Fluoroacetophenone has important application value in organic synthesis, and is commonly used as fluorination reagent, catalyst and intermediate. It is commonly used in the synthesis of drugs, dyes and chemicals.
Method:
A common method for preparing 3 '-Bromo-2'-Fluoroacetophenone is obtained by reacting acetophenone with bromine and hydrogen fluoride. Acetophenone was first added to the reaction vessel, then hydrogen fluoride was gradually added, and finally bromine was gradually added. After completion of the reaction, isolation and purification of the product are carried out.
Safety Information:
1. 3 '-Bromo-2'-Fluoroacetophenone should pay attention to fire prevention and ventilation during use and storage.
2. Inhalation and contact with skin may cause irritation and respiratory problems, so appropriate protective equipment should be worn during operation.
3. If ingested or in contact with eyes, rinse immediately with plenty of water and seek medical attention.
4. Please take care to properly store and handle the compound and avoid contact with strong oxidants and flammable materials.
Last Update：2024-04-09 20:49:11
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CAS: 161957-61-5
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CAS: 161957-61-5
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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