3,3'-Diaminobenzidine

3,3'-Diaminobenzidine - Names and Identifiers

Name	3,3'-Diaminobenzidine
Synonyms	Diaminobenzidine TIMTEC-BB SBB008427 3,3-Diaminobenzidine 3,3'-Diaminobenzidine 3,3,4,4-Biphenyltetramine 3,4,3,4-Tetraaminobiphenyl biphenyl-3,3',4,4'-tetramine 3,3',4,4'-Biphenyltetraamine 3,3'-Diaminobenzidine Factory 3,3'-Diaminobenzidine IN STOCK biphenyl-3,3,4,4-tetrayltetraamine 3,3'-Diaminobenzidine COA TDS MSDS 3,3',4,4'-[1,1'-Biphenyl]tetraamine 1,1'-Biphenyl-3,3',4,4'-tetrakisamine 3,3μ,4,4μ-Biphenyltetramine, 3,3μ,4,4μ-Tetraaminobiphenyl, DAB
CAS	91-95-2
EINECS	202-110-6
InChI	InChI=1/C12H14N4/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6H,13-16H2
InChIKey	HSTOKWSFWGCZMH-UHFFFAOYSA-N

3,3'-Diaminobenzidine - Physico-chemical Properties

Molecular Formula	C12H14N4
Molar Mass	214.27
Density	1.1726 (rough estimate)
Melting Point	175-177°C(lit.)
Boling Point	344.41°C (rough estimate)
Flash Point	12 °C
Water Solubility	0.55 g/L (20 ºC)
Solubility	0.55g/l
Vapor Presure	1.95E-09mmHg at 25°C
Appearance	Solid
Color	Crystals from MeOH
BRN	1212988
pKa	4.39±0.10(Predicted)
PH	7 (1g/l, H2O, 20℃)
Storage Condition	room temp
Stability	Stability Moisture and light sensitive. Incompatible with strong oxidizing agents.
Sensitive	Light Sensitive
Refractive Index	1.5000 (estimate)
MDL	MFCD00007725
Physical and Chemical Properties	Melting point 176-180°C water-soluble 0.55g/L (20°C)
Use	Monomer for use as a high-temperature-resistant polymer

3,3'-Diaminobenzidine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R22 - Harmful if swallowed R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R68 - Possible risk of irreversible effects R45 - May cause cancer R67 - Vapors may cause drowsiness and dizziness R37 - Irritating to the respiratory system R34 - Causes burns R11 - Highly Flammable R8 - Contact with combustible material may cause fire
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. S53 - Avoid exposure - obtain special instructions before use. S16 - Keep away from sources of ignition.
UN IDs	UN 3316 9
WGK Germany	1
RTECS	DV8750000
FLUKA BRAND F CODES	8-10-23
TSCA	Yes
HS Code	29214200
Toxicity	LDLo orl-rat: 3000 mg/kg CNREA8 26,619,66

3,3'-Diaminobenzidine - Reference

Reference

1. Cheng Juan, Li Qi, Zhang Hong, Song Shangguang, Wang Li, Li Cuihong, Xia Jingping, Ren Lihong. Effect of Chuyi Jiedu Fang on serum CD4 ~ and CD8 ~ T cells in recurrent herpes simplex keratitis rat model [J]. Chinese Journal of Ophthalmology of traditional Chinese medicine, 2018,28(05):292-296.
2. Yang Jingpeng, Song Yunbo, Li June, et al. Selenium-enriching ability of lactic acid bacteria and evaluation of its biological activity in vitro [J]. Chinese Journal of Food Science, 2019 019(001):171-182.
3. Yang Xin, Chen Li, Yang Shuangquan, Lu Hongmei, Zhang Zhu, Yang Hua Lian, Meng Yang, Wei Jianmin. Isolation, screening and identification of selenium-enriched yeast from Mulberry orchard in Kaiyang area [J]. Food and Fermentation Industry, 2020,46(24):66-73.
4. [IF = 6.331] Yanan Zhang et al."FeMoO4 Nanospheres-based Nanozymatic colorometry for Rapid and Sensitive Pyrophosphate Detection." J Mater Chem B. 2021 Dec;:

3,3'-Diaminobenzidine - Reference Information

NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Application	3,3 '-diaminobenzidine can be used as intermediates in organic synthesis and pharmaceutical intermediates, mainly used in laboratory research and development process and chemical production process.
Application	monomer used as high temperature resistant polymer
production method	(1)3,3 '-dichlorobenzidine as raw material, under the action of copper catalyst, reaction with ammonia;(2) using benzidine as raw material, reacting with acetic acid to generate biphenyl diacetamide, then reacting with nitric acid to generate 3,3'-dinitro-biphenyl diacetamide, in aqueous sulfuric acid hydrolysis, 3,3 '-dinitrobenzidine, and finally with sodium sulfide reduction, or catalytic hydrogenation reduction.
category	toxic substances
toxicity grade	poisoning
Acute toxicity	oral-rat LDL0: 3000 mg/kg; Oral-mouse LD50: 1834 mg/kg
flammability hazard characteristics	flammability; Toxic NOx smoke from combustion
storage and transportation characteristics	warehouse ventilation and low temperature drying
fire extinguishing agent	dry powder, foam, sand, carbon dioxide, water mist