3,3-Difluorocyclobutanol - D11666 - Names and Identifiers
3,3-Difluorocyclobutanol - D11666 - Physico-chemical Properties
Molecular Formula | C4H6F2O
|
Molar Mass | 108.09 |
Density | 1.27±0.1 g/cm3(Predicted) |
Boling Point | 108.1±40.0 °C(Predicted) |
pKa | 13.36±0.40(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
3,3-Difluorocyclobutanol - D11666 - Risk and Safety
3,3-Difluorocyclobutanol - D11666 - Introduction
3,3-difluorocyclobutan-1-ol is an organic compound with the chemical formula C4H6F2O. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3,3-difluorocyclobutan-1-ol is a colorless liquid.
-Boiling point: Its boiling point is 116-117 ℃, which can be volatilized at atmospheric pressure.
-Density: Its density is about 1.26 g/mL.
-Solubility: 3,3-difluorocyclobutan-1-ol has poor solubility in water, but has better solubility in some organic solvents (such as ethers and ketones).
-Chemical properties: It can undergo esterification and electrophilic substitution reactions with other compounds.
Use:
- 3,3-difluorocyclobutan-1-ol is commonly used as an important intermediate in organic synthesis and can be used to synthesize various pesticides, pharmaceuticals and chemicals.
-It can also be used as a photosensitive dye for laser photography and laser printing.
Preparation Method:
- 3,3-difluorocyclobutan-1-ol can be prepared by the following methods: First, chlorobutanone is reacted with hydrogen fluoride to obtain fluorobutanone, and then fluorobutanone is reacted with a base (such as an alkali metal hydroxide) to generate 3,3-difluorocyclobutanone. Finally, the resulting 3,3-difluorocyclobutanone is hydrolyzed under acidic conditions to give 3,3-difluorocyclobutan-1-ol.
Safety Information:
- 3,3-difluorocyclobutan-1-ol is an organic fluorine compound, which has certain toxicity, so it is necessary to pay attention to safety when using and handling.
-It may cause irritation to the eyes, skin and respiratory system, and may affect the central nervous system.
-Wear appropriate protective equipment such as chemical protective gloves, safety glasses and respiratory protective equipment during use.
-Avoid prolonged exposure to 3,3-difluorocyclobutan-1-ol vapor, and ensure that it is operated in a well-ventilated place.
-After use, keep the remaining 3,3-difluorocyclobutan-1-ol properly and avoid contact with fire and oxidizing agents.
Last Update:2024-04-09 21:01:54