3,3-bis(fluoromethyl)oxetane
3,3-bis(fluoromethyl)oxetane
CAS: 338-61-4
Molecular Formula: C5H8F2O
3,3-bis(fluoromethyl)oxetane - Names and Identifiers
| Name | 3,3-bis(fluoromethyl)oxetane |
| Synonyms | 3,3-bis(fluoromethyl)oxetane Oxetane, 3,3-bis(fluoroMethyl)- |
| CAS | 338-61-4 |
| InChI | InChI=1/C5H8F2O/c6-1-5(2-7)3-8-4-5/h1-4H2 |
3,3-bis(fluoromethyl)oxetane - Physico-chemical Properties
| Molecular Formula | C5H8F2O |
| Molar Mass | 122.11 |
| Density | 1.076g/cm3 |
| Boling Point | 153.328°C at 760 mmHg |
| Flash Point | 52.532°C |
| Vapor Presure | 4.294mmHg at 25°C |
| Refractive Index | 1.36 |
3,3-bis(fluoromethyl)oxetane - Introduction
3,3-bis(fluoromethyl)oxetane is an organic compound with the chemical formula C5H6F2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3,3-bis(fluoromethyl) is oxetane a colorless liquid.
-Density: 0.943g/cm³ (20 ℃)
-Boiling point: 80-82 ℃
-Melting point:-129 ℃
-Solubility: 3,3-bis(fluoromethyl)oxetane is soluble in many organic solvents.
Use:
- 3,3-bis(fluoromethyl)oxetane is often used as an important synthetic intermediate for the preparation of compounds such as pharmaceuticals and pesticides.
-It is also a potential high energy density compound, which is studied as a component of propellants and explosives.
Preparation Method:
3,3-bis(fluoromethyl)oxetane is usually prepared by the following steps:
1. First, methylfluoroacetone (methyl-2,2-difluoroacetate) is reacted with cyclobutane alcohol to obtain cyclobutane ketone (oxetanone).
2. Then, cyclobutanone is reacted with sodium fluoride (NaF) or hydrofluoric acid (HF) to obtain 3,3-bis(fluoromethyl)oxetane.
Safety Information:
- 3,3-bis(fluoromethyl)oxetane irritating and may be harmful to the eyes and skin.
-Appropriate safety precautions should be taken during use and storage, including wearing appropriate protective equipment and providing good ventilation.
-When exposed to this compound, immediately rinse the affected area with plenty of water and seek medical help.
- 3,3-bis(fluoromethyl)oxetane should be stored in a sealed container, away from fire and oxidizing agents.
Nature:
-Appearance: 3,3-bis(fluoromethyl) is oxetane a colorless liquid.
-Density: 0.943g/cm³ (20 ℃)
-Boiling point: 80-82 ℃
-Melting point:-129 ℃
-Solubility: 3,3-bis(fluoromethyl)oxetane is soluble in many organic solvents.
Use:
- 3,3-bis(fluoromethyl)oxetane is often used as an important synthetic intermediate for the preparation of compounds such as pharmaceuticals and pesticides.
-It is also a potential high energy density compound, which is studied as a component of propellants and explosives.
Preparation Method:
3,3-bis(fluoromethyl)oxetane is usually prepared by the following steps:
1. First, methylfluoroacetone (methyl-2,2-difluoroacetate) is reacted with cyclobutane alcohol to obtain cyclobutane ketone (oxetanone).
2. Then, cyclobutanone is reacted with sodium fluoride (NaF) or hydrofluoric acid (HF) to obtain 3,3-bis(fluoromethyl)oxetane.
Safety Information:
- 3,3-bis(fluoromethyl)oxetane irritating and may be harmful to the eyes and skin.
-Appropriate safety precautions should be taken during use and storage, including wearing appropriate protective equipment and providing good ventilation.
-When exposed to this compound, immediately rinse the affected area with plenty of water and seek medical help.
- 3,3-bis(fluoromethyl)oxetane should be stored in a sealed container, away from fire and oxidizing agents.
Last Update：2024-04-09 21:01:54
