3,4,5,2',3',4'-Hexahydroxybenzophenone

3,4,5,2',3',4'-Hexahydroxybenzophenone - Names and Identifiers

Name	3,4,5,2',3',4'-Hexahydroxybenzophenone
Synonyms	adlone Exifone EXIFONE 4-galloylpyrogallol 3,4,5,2',3',4'-Hexahydroxybenzophenone 3,4,5,2',3',4'-HEXAHYDROXYBENZOPHENONE 2,3,3',4,4',5'-HEXAHYDROXYBENZOPHENONE 2,3,4,3',4',5'-HEXAHYDROXY BENZOPHENONE (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-methanon (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone
CAS	52479-85-3
EINECS	257-945-9
InChI	InChI=1/C13H10O7/c14-7-2-1-6(11(18)13(7)20)10(17)5-3-8(15)12(19)9(16)4-5/h1-4,14-16,18-20H

3,4,5,2',3',4'-Hexahydroxybenzophenone - Physico-chemical Properties

Molecular Formula	C13H10O7
Molar Mass	278.21
Density	1.759±0.06 g/cm3(Predicted)
Melting Point	245°C
Boling Point	674.6±55.0 °C(Predicted)
Flash Point	375.8°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	8.11E-19mmHg at 25°C
Appearance	Solid
Color	Yellow
Merck	3915
pKa	6.99±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.795
MDL	MFCD00082966
Physical and Chemical Properties	Melting Point: 245°C

3,4,5,2',3',4'-Hexahydroxybenzophenone - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
RTECS	PC4995000
Toxicity	LD50 in rats (g/kg): 0.355 i.p.; 1.425 orally (Gazave)

3,4,5,2',3',4'-Hexahydroxybenzophenone - Reference Information

use

thinking enhancer. Used for Alzheimer's disease and Parkinson's disease.

production method

16g gallic acid, 20g phloroglucinol, 35g anhydrous zinc chloride and 100ml phosphorus oxychloride were reacted at 55~60 ℃ for 2.5h. Below 20 ℃, slowly pour into 1L of ice water. After standing for 2h, filter, wash with water (2 × 150 m1), 1% sodium bicarbonate (2 × 50 m1) and water (3 × 100 m1) to a Ph value of about 5. Dissolve 150ml of 95% ethanol, decolorization and filtration with activated carbon. Add 150ml of water and place at 10 ℃ for 4 hours. Filtration, small amount of deionized water washing, drying to obtain epicenzophenone, the yield is 49.1%.

Last Update：2024-04-09 02:00:09