3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER - Names and Identifiers
Name | 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane
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Synonyms | 5-Trifluorophenyl)-4 2-(3,4,5-Trifluorophenyl)-4,4,5,5-tetramethyl- 3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER 3,4,5-Trifluorobenzeneboronic acid pinacol ester 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane 4,4,5,5-TetraMethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane 2-(3,4,5-TRIFLUOROPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 2-(3,4,5-TRIFLUOROBENZENE)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 1,3,2-Dioxaborolane,4,4,5,5-tetraMethyl-2-(3,4,5-trifluorophenyl)- 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-
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CAS | 827614-70-0
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InChI | InChI=1/C12H14BF3O2/c1-11(2)12(3,4)18-13(17-11)7-5-8(14)10(16)9(15)6-7/h5-6H,1-4H3 |
3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER - Physico-chemical Properties
Molecular Formula | C12H14BF3O2
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Molar Mass | 258.04 |
Density | 1.17g/cm3 |
Boling Point | 285°C at 760 mmHg |
Flash Point | 126.2°C |
Vapor Presure | 0.00494mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.4520 to 1.4560 |
3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER - Introduction
4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane is an organic compound with the chemical formula C13H13BF3O2. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane is a colorless or slightly yellow liquid.
-Melting point: Its melting point is between -5°C and -7°C.
-Boiling point: Its boiling point is between 190°C and 192°C.
-Density: Its density is about 1.18 g/cm ^ 3.
-Solubility: It is soluble in non-polar solvents, such as esters, ethers and aromatic hydrocarbons.
Use:
- 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane is commonly used as a boronic ester reagent in organic synthesis. It can be used as a synthetic intermediate to participate in a series of synthetic reactions of organic compounds, such as reduction, coupling, oxidation and other reactions.
-It can also be used as an organoboron reagent in a ligand or catalyst to participate in metal-catalyzed reactions.
Preparation Method:
The preparation method of -4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane is relatively complicated, and it usually needs to be synthesized through multi-step reactions.
-A common preparation method is to use the ester exchange reaction of the ester of the alcohol ester as the starting material, using boric acid and the corresponding aryl trifluoroborate ester.
Safety Information:
- 4,4,5,5-tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane There are currently no detailed safety data publicly available. General laboratory safety practices should be followed in handling and use.
-When handling and handling organic compounds, appropriate personal protective measures must be taken, such as wearing protective glasses, gloves and laboratory coats, avoiding inhalation, contact with skin and ingestion.
-The compound should be stored in a cool, dry place, away from fire sources and oxidants, and avoid contact with strong acids, strong bases and strong oxidants.
Last Update:2024-04-10 22:29:15