3,4-Dehydro Cilostazol-d11 - Names and Identifiers
3,4-Dehydro Cilostazol-d11 - Physico-chemical Properties
Molecular Formula | C20H25N5O2
|
Molar Mass | 367.4448 |
Melting Point | 177-180°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Appearance | Solid |
Color | White |
Storage Condition | -20°C Freezer |
3,4-Dehydro Cilostazol-d11 - Introduction
Cilostazol-d11 3,4-dehydro (3,4-dehydrothialofezine-d11) is a compound with a specific isotopic label. It is prepared by isotopic labeling of Cilostazol (thialofezine). Thialofezine is an anti-platelet aggregation drug used to prevent thrombosis and relieve vasospasm.
3,4-dehydro Cilostazol-d11 is commonly used in pharmacokinetic studies, drug absorption, distribution, metabolism, and excretion (ADME) studies. It can be used as an internal standard compound for quantitative analysis to determine the metabolic processes of Cilostazol in the body.
The method for preparing 3,4-dehydro Cilostazol-d11 is usually to introduce deuterium isotope into the molecular structure of Cilostazol. A specific preparation method may be deuteration of Cilostazol by using a suitable deuteration reagent, such as heavy water (D2O) or sodium deuteride (NaD), under suitable reaction conditions, form 3,4-dehydro Cilostazol-d11.
In terms of safety, the toxicity and safety of 3,4-Dehydro Cilostazol-d11 are similar to those of Cilostazol. However, due to its non-isotopically labeled nature, its use and handling require special care and caution. The use of 3,4-Dehydro Cilostazol-d11 requires strict adherence to laboratory safety procedures and to ensure proper storage and handling.
Last Update:2024-04-09 21:04:16